The role of oxidized phospholipids in atherosclerosis
JA Berliner, N Leitinger, S Tsimikas - Journal of lipid research, 2009 - ASBMB
There is increasing evidence that oxidized phospholipids (OxPLs) play an important role in
atherosclerosis. These phospholipids accumulate in human and mouse lesions. Specific …
atherosclerosis. These phospholipids accumulate in human and mouse lesions. Specific …
Role of phospholipid oxidation products in atherosclerosis
S Lee, KG Birukov, CE Romanoski… - Circulation …, 2012 - Am Heart Assoc
There is increasing clinical evidence that phospholipid oxidation products (Ox-PL) play a
role in atherosclerosis. This review focuses on the mechanisms by which Ox-PL interact with …
role in atherosclerosis. This review focuses on the mechanisms by which Ox-PL interact with …
[HTML][HTML] Oxidized phospholipids: from molecular properties to disease
GO Fruhwirth, A Loidl, A Hermetter - Biochimica et Biophysica Acta (BBA) …, 2007 - Elsevier
Oxidized lipids are generated from (poly) unsaturated diacyl-and alk (en) ylacyl
glycerophospholipids under conditions of oxidative stress. The great variety of reaction …
glycerophospholipids under conditions of oxidative stress. The great variety of reaction …
Oxidized phospholipids as a new landmark in atherosclerosis
H Itabe - Progress in lipid research, 1998 - Elsevier
It is thought that high concentrations of plasma low density lipoprotein (LDL) are correlated
with the occurrence of atherosclerosis. Although no intimal thickening is observed in the …
with the occurrence of atherosclerosis. Although no intimal thickening is observed in the …
Oxidized phospholipids and isoprostanes in atherosclerosis
JL Witztum, JA Berliner - Current opinion in lipidology, 1998 - journals.lww.com
Lipid oxidation has been shown to be a prominent feature of atherosclerosis. The presence
of isoprostanes and other lipid oxidation products has been clearly demonstrated in lesions …
of isoprostanes and other lipid oxidation products has been clearly demonstrated in lesions …
Role of oxidized low density lipoprotein in atherogenesis.
JL Witztum, D Steinberg - The Journal of clinical …, 1991 - Am Soc Clin Investig
Evidence to support an important role of oxidative modification in mediating the
atherogenicity of LDL continues to grow. New hypotheses suggest mechanisms by which Ox …
atherogenicity of LDL continues to grow. New hypotheses suggest mechanisms by which Ox …
The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis.
S Parthasarathy, D Steinberg… - Annual review of medicine, 1992 - europepmc.org
Hypercholesterolemia is a major risk for atherogenesis. Recent evidence suggests that
oxidative modification of the major cholesterol-carrying lipoprotein, low-density lipoprotein …
oxidative modification of the major cholesterol-carrying lipoprotein, low-density lipoprotein …
The oxidative modification hypothesis of atherosclerosis: the comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma
K Nakajima, T Nakano, A Tanaka - Clinica Chimica Acta, 2006 - Elsevier
A tremendous number of articles on oxidized LDL (Ox-LDL) and scavenger receptor in
macrophage have been published since Steinberg proposed Ox-LDL hypothesis as the …
macrophage have been published since Steinberg proposed Ox-LDL hypothesis as the …
Evidence for lipid peroxidation in atherosclerosis
JJ Piotrowski, GC Hunter, CD Eskelson, MA Dubick… - Life sciences, 1990 - Elsevier
Lipid peroxidation may play a significant role in the initiation and progression of
atherosclerotic plaque. Freshly harvested normal and atherosclerotic human aortic tissue …
atherosclerotic plaque. Freshly harvested normal and atherosclerotic human aortic tissue …
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions
VN Bochkov, M Philippova, O Oskolkova… - Circulation …, 2006 - Am Heart Assoc
Angiogenesis is a common feature observed in advanced atherosclerotic lesions. We
hypothesized that oxidized phospholipids (OxPLs), which accumulate in atherosclerotic …
hypothesized that oxidized phospholipids (OxPLs), which accumulate in atherosclerotic …