Betulinic acid, a plant secondary metabolite, has gained significant attention due to its
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …

Background Tumor, is one of the major reason for human death, due to its widespread
occurrence. Betulinic acid derivatives have attracted considerable attention as cancer …

Background Development of betulinic acid derivatives for clinical use has been hampered
by adverse pharmacological and physico‐chemical characteristics of this class of …

The pursual of novel anticancer molecules from natural sources has gained worthwhile
appreciation, and a significant fraction of conceptual knowledge has revolutionized our …

In vitro and in vivo pharmacological screening of Betulinic acid (BA) and five dihydro-BA
derivatives modified at C-3 position [4-nitrobenzyl-oximino (1), 2-4-difluoro-benzoyloxy (2), 2 …

Betulinic acid (BA), a natural compound with a lupan skeleton, has been highly investigated
in the past decade for a plethora of beneficial properties, including anti-cancer, anti …

Background Betulinic acid (BA), a member of pentacyclic triterpenes has shown important
biological activities like anti-bacterial, anti-malarial, anti-inflammatory and most interestingly …

Background Betulinic acid (BA) is a complex lupane triterpenoid with unique antineoplastic
activity. However, its antiproliferative activity is far from satisfaction. In order to improve its …

Betulinic acid (BA), a pentacyclic triterpene isolated from birch bark and other plants,
selectively inhibits the growth of human cancer cell lines. However, the poor potency of BA …

Betulinic acid is a natural compound with high in vitro cytotoxicity toward many cancer cells.
However, the poor water solubility of this compound hampers an effective in vivo cancer …