Highlights•Immune instructive materials are increasingly used for immunotherapies.•
Polymers with distinct physical or chemical cues can direct immune cell activation.•Artificial …

Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …

Inflammation is a crucial part of wound healing and pathogen clearance. However, it can
also play a role in exacerbating chronic diseases and cancer progression when not …

Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Immune responses are directed by the complex interactions of different cell types, including
T cells and Natural Killer (NK) cells, with a key type of interaction being the formation of …

Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …