Diarylpropionitrile (DPN), a selective agonist for estrogen receptor β (ERβ), has been
reported to regulate various hormonal responses through activation of ERβ in tissues …

Protocatechuic aldehyde (PA) is a naturally occurring phenolic compound that is a potent
inhibitor of mushroom tyrosinase. However, the molecular mechanisms of the anti …

Melanin protects our skin from harmful ultraviolet (UV) radiation. However, when produced
in excess, it can cause hyperpigmentation disorders, such as melanoma, freckles, lentigo …

Melanin protects the skin against ultraviolet (UV) rays. It is produced in excess by UV
radiation, which causes skin disorders and pigmentation. Retinoic acid (RA) decreases the …

BACKGROUND: It is well known that melanin synthesis in melanoma cells is controlled by
melanogenic enzymes, which regulate the cAMP-PKA signaling pathway. Estrogen was …

The objectives of this study were to investigate the melanogenetic potentials of the naturally
occurring 7-hydroxy coumarin derivatives 7-hydroxy 5, 6-dimethoxycoumarin (7H-5, 6DM), 7 …

Diphlorethohydroxycarmalol (DPHC) is a marine polyphenolic compound derived from
brown alga Ishige okamurae. A previously study has suggested that DPHC possesses …

Aims To report the effects of a novel syringic-acid derivative,(R)-ethyl-2-acetamido-3-(4-
hydroxy-3, 5-dimethoxybenzoylthio) propanoate (EABTO), on melanin synthesis and to …

As an active compound, psoralen is present in various Chinese herbal medicines and has
exhibited significant activity in skin disease treatment. Its derivative 8-methoxypsoralan (8 …

Caffeic acid phenethyl ester (1), a natural compound found in various plants and propolis, is
a well-known anti-inflammatory, immunomodulatory, and cytotoxic agent. The present study …