[HTML][HTML] Identification of the common neurobiological process disturbed in genetic and non-genetic models for autism spectrum disorders

S Malijauskaite, AK Sauer, SE Hickey… - Cellular and Molecular …, 2022 - Springer
Autism spectrum disorders (ASD) are neurodevelopmental disorders. Genetic factors, along
with non-genetic triggers, have been shown to play a causative role. Despite the various …

The need for a comprehensive molecular characterization of autism spectrum disorders

JAC Broek, E Brombacher… - International Journal …, 2014 - academic.oup.com
Autism spectrum disorders (ASD) are a heterogeneous group of disorders which have
complex behavioural phenotypes. Although ASD is a highly heritable neuropsychiatric …

[HTML][HTML] Synaptopathology involved in autism spectrum disorder

S Guang, N Pang, X Deng, L Yang, F He… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

[HTML][HTML] Genetic aspects of autism spectrum disorders: insights from animal models

S Banerjee, M Riordan, MA Bhat - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a complex neurodevelopmental disorder that display
a triad of core behavioral deficits including restricted interests, often accompanied by …

Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities

HY Zoghbi, MF Bear - Cold Spring Harbor perspectives …, 2012 - cshperspectives.cshlp.org
The discovery of the genetic causes of syndromic autism spectrum disorders and intellectual
disabilities has greatly informed our understanding of the molecular pathways critical for …

Using Multitissue Multiomics Systems Biology to Understand Tissue-specific Networks of Autism Spectrum Disorders

CE Gill - 2024 - escholarship.org
The genetic heterogeneity of autism spectrum disorder (ASD) has been a long-standing
obstacle in our understanding of the pathogenic mechanisms of the disease, as the genetic …

[HTML][HTML] Network-based integrative analysis of genomics, epigenomics and transcriptomics in autism spectrum disorders

N Di Nanni, M Bersanelli, FA Cupaioli… - International Journal of …, 2019 - mdpi.com
Current studies suggest that autism spectrum disorders (ASDs) may be caused by many
genetic factors. In fact, collectively considering multiple studies aimed at characterizing the …

Neurogenomic pathway of autism spectrum disorders: linking germline and somatic mutations to genetic-environmental interactions

SG Vorsanova, YB Yurov, IY Iourov - Current bioinformatics, 2017 - ingentaconnect.com
Bioinformatic approaches have been extensively applied in genetic and genomic studies of
autism spectrum disorders (ASD). However, since this disorder has a distinct albeit complex …

[HTML][HTML] Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes

L Diaz-Beltran, FJ Esteban, M Varma, A Ortuzk… - BMC genomics, 2017 - Springer
Background Numerous studies have highlighted the elevated degree of comorbidity
associated with autism spectrum disorder (ASD). These comorbid conditions may add …

[HTML][HTML] Determination of molecular signatures and pathways common to brain tissues of autism spectrum disorder: insights from comprehensive bioinformatics …

SA Bristy, AMH Islam, KMS Andalib, U Khan… - Informatics in Medicine …, 2022 - Elsevier
Autism spectrum disorder (ASD) is a collection of neurological disabilities marked by
difficulties with behavior, speech, language, and interaction. It is a complicated and …