The capsaicin receptor, transient receptor potential vanilloid type 1 ion channel (TRPV1),
has been identified as a polymodal transducer molecule on a sub-set of primary sensory …

Linopirdine is a well known blocker of voltage-gated potassium channels from the Kv7 (or
KCNQ) family that generate the so called M current in mammalian neurons. Kv7 subunits are …

Abstract The Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel is expressed
mainly by sensory neurons that detect noxious stimuli from the environment such as high …

A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

Some like it hot: spicing up ion channels | Nature Skip to main content Thank you for visiting
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The capsaicin receptor TRPV1 has been widely characterized in the sensory system as a
key component of pain and inflammation. A large amount of evidence shows that TRPV1 is …

The capsaicin receptor, TRPV1 (VR1), is a sensory neuron-specific ion channel that serves
as a polymodal detector of pain-producing chemical and physical stimuli. Extracellular Ca2+ …

Vanilloids such as capsaicin and resiniferatoxin are highly selective and potent activators for
transient receptor potential vanilloid subfamily, member 1, a nociceptor for heat and pain …

Capsaicin is a potent agonist of the Transient Receptor Potential Vanilloid type 1 (TRPV1)
channel and is a common component found in the fruits of the genus Capsicum plants …

The transient receptor potential vanilloid type-2 (TRPV2) protein is a nonselective Ca2+
permeable channel member of the TRPV subfamily, still considered an orphan TRP channel …