Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: inhibition of ribonucleotide reductase activity

P Saiko, M Pemberger, Z Horvath… - Oncology …, 2008 - spandidos-publications.com
Abstract Resveratrol (3, 4', 5-trihydroxy-trans-stilbene; RV), an ingredient of wine, exhibits a
broad spectrum of antiproliferative effects against human cancer cells. In order to enhance …

Resveratrol induces autophagy-dependent apoptosis in HL-60 cells

Y Fan, JF Chiu, J Liu, Y Deng, C Xu, J Zhang, G Li - BMC cancer, 2018 - Springer
Background All known mechanisms of apoptosis induced by resveratrol act through cell
cycle arrest and changes in mitochondrial membrane potential. It is currently unknown …

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms

M Athar, JH Back, L Kopelovich, DR Bickers… - Archives of biochemistry …, 2009 - Elsevier
Plant-derived polyphenolic compounds, such as the stilbene resveratrol (trans-3, 4′, 5-
trihydroxystilbene), have been identified as potent anti-cancer agents. Extensive in vitro …

Resveratrol-induced apoptosis in human breast cancer cells is mediated primarily through the caspase-3-dependent pathway

M Alkhalaf, A El-Mowafy, W Renno, O Rachid… - Archives of medical …, 2008 - Elsevier
BACKGROUND: Resveratrol (RSVL), a nontoxic natural compound found in a wide variety
of plants with known antioxidant and anti-inflammatory properties, is emerging as a potent …

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis

H Zhao, L Han, Y Jian, Y Ma, W Yan… - OncoTargets and …, 2018 - Taylor & Francis
Background Resveratrol is known as a natural phytoalexin found in grapes and wine, which
has significant antitumor activity under in vitro and in vivo conditions. In recent years, great …

The effect of resveratrol, its naturally occurring derivatives and tannic acid on the induction of cell cycle arrest and apoptosis in rat C6 and human T98G glioma cell …

M Zielińska-Przyjemska, M Kaczmarek… - Toxicology in Vitro, 2017 - Elsevier
Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a potent chemopreventive and
potentially cancer therapeutic agent. Since rapid metabolism limits resveratrol …

Selective growth inhibition of human leukemia and human lymphoblastoid cells by resveratrol via cell cycle arrest and apoptosis induction

SK Lee, W Zhang, BJS Sanderson - Journal of agricultural and …, 2008 - ACS Publications
There is great interest in the potential chemopreventive activity of resveratrol against human
cancers. However, there are conflicting results on its growth inhibitory effect on normal cells …

Different effect of resveratrol to induction of apoptosis depending on the type of human cancer cells

M Takashina, S Inoue, K Tomihara… - International …, 2017 - spandidos-publications.com
The effect of resveratrol on various human cancer cells was investigated with special focus
on apoptotic cell death, in an attempt to further characterize its mechanism of action. There …

Apoptotic cell death induced by resveratrol is partially mediated by the autophagy pathway in human ovarian cancer cells

F Lang, Z Qin, F Li, H Zhang, Z Fang, E Hao - PloS one, 2015 - journals.plos.org
Resveratrol (trans-3, 4, 5'–trihydroxystilbene) is an active compound in food, such as red
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …

Resveratrol: potential as anticancer agent

JK Aluyen, QN Ton, T Tran, AE Yang… - Journal of dietary …, 2012 - Taylor & Francis
Background: Cancer is one of the leading causes of deaths in the world. Current
chemotherapeutic agents are associated with serious side effects in patients therefore …