Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

[HTML][HTML] Resveratrol induces apoptosis in murine prostate cancer cells via hypoxia-inducible factor 1-alpha (HIF-1α)/reactive oxygen species (ROS)/P53 signaling

D Wang, Z Gao, X Zhang - Medical Science Monitor: International …, 2018 - ncbi.nlm.nih.gov
Background Resveratrol, a polyphenol found on the surface of red fruits, is able to suppress
many kinds of malignancies. Nevertheless, its mechanism of action is not yet clear …

Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies

BB Aggarwal, A Bhardwaj, RS Aggarwal… - Anticancer …, 2004 - ar.iiarjournals.org
Resveratrol, trans-3, 5, 4'-trihydroxystilbene, was first isolated in 1940 as a constituent of the
roots of white hellebore (Veratrum grandiflorum O. Loes), but has since been found in …

Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines

AK Joe, H Liu, M Suzui, ME Vural, D Xiao… - Clinical cancer …, 2002 - AACR
Purpose: We examined the effects of the phytochemical resveratrol in six human cancer cell
lines (MCF7, SW480, HCE7, Seg-1, Bic-1, and HL60). Experimental Design and Results …

Resveratrol: from basic studies to bedside

A Borriello, D Bencivenga, I Caldarelli… - Advances in Nutrition …, 2014 - Springer
Plants produce a remarkable amount of low molecular mass natural products endowed with
a large array of pivotal biological activities. Among these molecules, resveratrol (3, 5, 4' …

[HTML][HTML] Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells

S Kumar, E Eroglu, JA Stokes III, K Scissum-Gunn… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Found in the skins of red fruits, including grapes, resveratrol (RES) is a polyphenolic
compound with cancer chemopreventive activity. Because of this activity, it has gained …

Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells

Y Kim, BT Choi, YT Lee, DI Park… - Oncology …, 2004 - spandidos-publications.com
Resveratrol, which is found in grapes and wine, has been reported to have a variety of
important pharmacological effects including anti-inflammatory, anti-platelet, and anti …

Resveratrol as an anti-cancer agent: A review

A Rauf, M Imran, MS Butt, M Nadeem… - Critical reviews in …, 2018 - Taylor & Francis
Owing to their antimicrobial, antioxidant, and anti-inflammatory activity, grapes (Vitis vinifera
L.) are the archetypal paradigms of fruits used not only for nutritional purposes, but also for …

Dual effects of resveratrol on cell death and proliferation of colon cancer cells

Á San Hipólito-Luengo, A Alcaide… - Nutrition and …, 2017 - Taylor & Francis
Colorectal cancer remains a main cause of deaths worldwide, and novel agents are being
searched to treat this disease. Polyphenols have emerged as promising therapeutic tools in …

Effects and mechanisms of resveratrol for prevention and management of cancers: An updated review

SX Wu, RG Xiong, SY Huang, DD Zhou… - Critical Reviews in …, 2023 - Taylor & Francis
Cancer is a severe public health problem. Resveratrol is a famous natural compound that
has various bioactivities, such as antioxidant, anti-inflammatory, antidiabetic and antiaging …