From French Paradox to cancer treatment: Anti-cancer activities and mechanisms of resveratrol

X Yang, X Li, J Ren - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene, RVT), a stilbenoid, polyphenol phytochemical
present in berries, grape, peanuts and wine. It has been suggested as a major contributor to …

Resveratrol induces cell‐cycle disruption and apoptosis in chemoresistant B16 melanoma

G Gatouillat, E Balasse… - Journal of cellular …, 2010 - Wiley Online Library
Resveratrol, a naturally occurring polyphenol, has been shown to possess chemopreventive
activities. In this study, we show that resveratrol (0–500 µM) inhibits the growth of a …

Resveratrol and cellular mechanisms of cancer prevention

Y Shukla, R Singh - Annals of the New York Academy of …, 2011 - Wiley Online Library
The use of novel and improved chemopreventive and chemotherapeutic agents for the
prevention and treatment of cancer is on the rise. Natural products have always afforded a …

[HTML][HTML] Anti-cancer properties of resveratrol: a focus on its impact on mitochondrial functions

L Kursvietiene, DM Kopustinskiene, I Staneviciene… - Antioxidants, 2023 - mdpi.com
Cancer is one of the most serious public health issues worldwide, demanding ongoing
efforts to find novel therapeutic agents and approaches. Amid growing interest in the …

[HTML][HTML] A review of resveratrol as a potent chemoprotective and synergistic agent in cancer chemotherapy

Q Xiao, W Zhu, W Feng, SS Lee, AW Leung… - Frontiers in …, 2019 - frontiersin.org
Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer

D Sareen, SR Darjatmoko, DM Albert, AS Polans - Molecular pharmacology, 2007 - ASPET
Resveratrol (RES), a natural plant polyphenol, has gained interest as a nontoxic
chemopreventive agent capable of inducing tumor cell death in a variety of cancer types …

Resveratrol and chemoprevention

SK Goswami, DK Das - Cancer letters, 2009 - Elsevier
Resveratrol is a phytoalexin, highly abundant in skins of red grapes and moderately
abundant in peanuts and blueberries. Originally a constituent of oriental medicines, it has …

Molecular mechanism of the chemopreventive effect of resveratrol

Z Dong - … Research/Fundamental and Molecular Mechanisms of …, 2003 - Elsevier
Chemoprevention is a promising approach to control human cancer. Resveratrol has been
shown to have a potent chemopreventive effect in multiple carcinogenesis models …

Resveratrol as an anticancer nutrient: molecular basis, open questions and promises

P Signorelli, R Ghidoni - The Journal of nutritional biochemistry, 2005 - Elsevier
The polyphenol resveratrol is an anticancer nutrient that was shown to inhibit cancer
initiation and promotion [Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW …

Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells

E Madan, S Prasad, P Roy, J George… - … and biophysical research …, 2008 - Elsevier
Resveratrol (trans-3, 4′, 5-trihydroxystilbene), a polyphenolic phytoalexin present mainly in
grapes, red wine and berries, is known to possess strong chemopreventive and anticancer …