Medullary tachykinin precursor 1 neurons promote rhythmic breathing

R Jean-Philippe, F Andreea, RL Horner, M Gaspard - eLife, 2023 - search.proquest.com
Rhythmic breathing is generated by neural circuits located in the brainstem. At its core is the
preBötzinger Complex (preBötC), a region of the medulla, necessary for the generation of …

Medullary tachykinin precursor 1 neurons promote rhythmic breathing

JP Rousseau, A Furdui, C da Silveira Scarpellini… - Elife, 2023 - elifesciences.org
Rhythmic breathing is generated by neural circuits located in the brainstem. At its core is the
preBötzinger Complex (preBötC), a region of the medulla, necessary for the generation of …

A tachykinin precursor 1 medullary circuit promoting rhythmic breathing

JP Rousseau, A Furdui, C da Silveira Scarpellini… - BioRxiv, 2023 - biorxiv.org
Rhythmic breathing is generated by neural circuits located in the brainstem. At its core is the
preBötzinger Complex (preBötC), a region of the medulla, necessary for the generation of …

Neurokinin receptor-expressing pre-botzinger complex neurons in neonatal mice studied in vitro

JA Hayes, CA Del Negro - Journal of neurophysiology, 2007 - journals.physiology.org
Breathing in mammals depends on inspiratory-related neural activity generated in the pre-
Bötzinger complex (preBötC), where neurokinin receptor-expressing neurons (NKR+) …

Fluorescent tagging of rhythmically active respiratory neurons within the pre-Bötzinger complex of rat medullary slice preparations

S Pagliardini, T Adachi, J Ren, GD Funk… - Journal of …, 2005 - Soc Neuroscience
Elucidation of the neuronal mechanisms underlying respiratory rhythmogenesis is a major
focal point in respiratory physiology. An area of the ventrolateral medulla, the pre-Bötzinger …

Pre-bötzinger complex neurokinin-1 receptor expressing neurons in primary cell culture

SM Johnson - Integration in Respiratory Control: From Genes to …, 2008 - Springer
Phenotypic identification of pre-Bötzinger complex (pre-BötC) neurons is vital to the
delineation of endogenous cellular properties involved in respiratory rhythm generation and …

Normal breathing requires preBötzinger complex neurokinin-1 receptor-expressing neurons

PA Gray, WA Janczewski, N Mellen… - Nature …, 2001 - nature.com
The normal breathing rhythm in mammals is hypothesized to be generated by neurokinin-1
receptor (NK1R)-expressing neurons in the preBötzinger complex (preBötC), a medullary …

Contribution of the respiratory network to rhythm and motor output revealed by modulation of GIRK channels, somatostatin and neurokinin-1 receptors

G Montandon, H Liu, RL Horner - Scientific reports, 2016 - nature.com
Breathing is generated by a respiratory network in the brainstem. At its core, a population of
neurons expressing neurokinin-1 receptors (NK1R) and the peptide somatostatin (SST) form …

State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing

A Doi, JM Ramirez - Journal of Neuroscience, 2010 - Soc Neuroscience
All neuronal networks are modulated by multiple neuropeptides and biogenic amines. Yet,
few studies investigate how different modulators interact to regulate network activity. Here …

Modulation of respiratory frequency by peptidergic input to rhythmogenic neurons in the preBotzinger complex

PA Gray, JC Rekling, CM Bocchiaro, JL Feldman - Science, 1999 - science.org
Neurokinin-1 receptor (NK1R) and μ-opioid receptor (μOR) agonists affected respiratory
rhythm when injected directly into the preBötzinger Complex (preBötC), the hypothesized …