[HTML][HTML] Mitochondria: Their relevance during oocyte ageing
J van der Reest, GN Cecchino, MC Haigis… - Ageing research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …
[HTML][HTML] Mitochondria in oocyte aging: current understanding
D Zhang, D Keilty, ZF Zhang… - Facts, views & vision in …, 2017 - ncbi.nlm.nih.gov
The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
factories for cells, are found in high numbers in oocytes, as they provide the energy for …
Oocyte mitochondria—Key regulators of oocyte function and potential therapeutic targets for improving fertility
The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …
production. This reliance on mitochondrial activity, together with the exclusively maternal …
Mitochondria in ovarian aging and reproductive longevity
Mitochondrial dysfunction is one of the hallmarks of aging. Consistently mitochondrial DNA
(mtDNA) copy number and function decline with age in various tissues. There is increasing …
(mtDNA) copy number and function decline with age in various tissues. There is increasing …
The contribution of mitochondrial function to reproductive aging
Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …
increased significantly in the last decade. While it is well established that women's …
Ovarian ageing: the role of mitochondria in oocytes and follicles
P May-Panloup, L Boucret… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND There is a great inter-individual variability of ovarian ageing, and almost
20% of patients consulting for infertility show signs of premature ovarian ageing. This …
20% of patients consulting for infertility show signs of premature ovarian ageing. This …
[HTML][HTML] Embryo and its mitochondria
P May-Panloup, M Boguenet, H El Hachem, PE Bouet… - Antioxidants, 2021 - mdpi.com
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …
to many other essential cellular functions. One of the unique characteristics of the …
Mitochondrial dysfunction and ovarian aging
I Kasapoğlu, E Seli - Endocrinology, 2020 - academic.oup.com
As women delay childbearing because of demographic and socioeconomic trends,
reproductive aging and ensuing ovarian dysfunction become increasingly more prevalent …
reproductive aging and ensuing ovarian dysfunction become increasingly more prevalent …
Reproductive aging is associated with decreased mitochondrial abundance and altered structure in murine oocytes
VA Kushnir, T Ludaway, RB Russ, EJ Fields… - Journal of assisted …, 2012 - Springer
Purpose To establish the phenotype of reproductive aging in our mouse model. To test the
hypotheses that reproductive aging is associated with a decrease in mitochondrial …
hypotheses that reproductive aging is associated with a decrease in mitochondrial …
Mitochondrial dysfunction and ovarian aging
Mitochondria are double‐membrane‐bound organelles that are responsible for the
generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in …
generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in …