Cellular senescence is a process that results from a variety of stresses, leading to a state of
irreversible growth arrest. Senescent cells accumulate during aging and have been …

Mitochondria are the energy producing dynamic double-membraned organelles essential
for cellular and organismal survival. A multitude of intra-and extra-cellular signals involved in …

STUDY QUESTION Do the extreme conditions of vitrification affect mitochondrial health and
reactive oxygen species (ROS) levels of human oocytes? SUMMARY ANSWER Vitrification …

The aging process is accompanied by the onset of disease and a general decline in
wellness. Insights into the aging process have revealed a number of cellular hallmarks of …

Mitochondria play a central role in the regulation of energy metabolism in oocytes and
preimplantation embryos, where the number and morphology of mitochondria and …

This review covers some novel findings on mitochondrial biochemistry and discusses
diseases due to mitochondrial DNA mutations as a model of the changes occurring during …

Mitochondria plays a complex multi-factorial role in the cell. In addition to their primary role
in ATP generation, the organelles sequester calcium and both generate and detoxify …

Mitochondria are organelles with vital functions in almost all eukaryotic cells. Often
described as the cellular 'powerhouses' due to their essential role in aerobic oxidative …

Mitochondria are deeply involved in the production of reactive oxygen species through one-
electron carriers in the respiratory chain; mitochondrial structures are also very susceptible …

Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …