HTLV-1 proviral load as an indicative marker of HAM/TSP: a systematic review of studies of patients with HAM/TSP

SS Bassi, R Coutinho, VN Olavarria, F Martin… - Retrovirology, 2014 - Springer
The diagnosis of HAM/TSP is based on criteria, as proposed by the World Health
Organization, revised in 1989. This primarily relies on diagnosis through laboratory criteria …

HTLV-1 proviral load of HAM/TSP patients according to new diagnostic criteria of HAM/TSP

MFR Grassi, VN Olavarria, RA Kruschewsky… - Retrovirology, 2011 - Springer
Methods 281 HTLV-1-infected patients from the HTLV reference center in Salvador, Brazil,
were followed from 2005 to 2008. Patients were classified as asymptomatic, possible …

HTLV-1 proviral load in cerebrospinal fluid may not be a good marker to differentiate asymptomatic carriers with high proviral load in blood from HAM/TSP patients

ML Martins, AB de Freitas Carneiro-Proietti… - Journal of …, 2018 - Springer
An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important
risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Long-term follow-up of HTLV-1 proviral load in asymptomatic carriers and in incident cases of HAM/TSP: what is its relevance as a prognostic marker for neurologic …

ML Martins, JC Guimarães, JG Ribas… - Journal of …, 2017 - Springer
Abstract HTLV-1 proviral load (pvl) is an important risk marker for HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP), but its value as prognostic marker is not …

Follow-up of HTLV-1 positive individuals in the GIPH cohort (1997-2013): Proviral load was not a prognostic marker for HAM/TSP

PC Gonçalves, GS Freitas, LCF Romanelli, FA Proietti… - Retrovirology, 2014 - Springer
Methods Quantification of HTLV-1 PVL was performed in 151 samples of 38 asymptomatic
carriers (AC) collected at different times during follow-up (6.1 to 14.8 years, mean 10) and in …

HTLV-1 proviral load in peripheral blood mononuclear cells quantified in 100 HAM/TSP patients: a marker of disease progression

S Olindo, A Lézin, P Cabre, H Merle, M Saint-Vil… - Journal of the …, 2005 - Elsevier
A high proviral load of human T cell lymphotropic virus type 1 (HTLV-1) in peripheral blood
mononuclear cells (PBMCs) has been reported in patients with HTLV-1-associated …

[HTML][HTML] Evolution of HTLV-1 proviral load in patients from Salvador, Brazil

VN Olavarria, AN Gomes, RA Kruschewsky… - Brazilian Journal of …, 2012 - SciELO Brasil
INTRODUCTION: Variations in human T cell lymphotropic virus type 1 (HTLV-1) proviral
load (PVL) in infected individuals over time are not well understood. Objective: To evaluate …

Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP

M Nagai, K Usuku, W Matsumoto, D Kodama… - Journal of …, 1998 - Taylor & Francis
In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we
measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a …

The clinical utility of HTLV-1 viral load measurement

MA Demontis, S Hilburn, GP Taylor - Retrovirology, 2011 - Springer
Methods Viral loads were quantified using a SYBR Green-based real-time quantitative
polymerase chain reaction, and expressed as a percentage of infected PBMCs. Results 1 …

Neurologic, clinical, and immunologic features in a cohort of HTLV-1 carriers with high proviral loads

SN Ferraz, GF Costa, JA Carneiro Neto, T Hebert… - Journal of …, 2020 - Springer
A high proviral load (PVL) is recognized as a risk factor for human T cell leukemia virus-1-
associated myelopathy/tropical spastic paraparesis (HAM/TSP), but there is a lack of …