Paternal cocaine in mice alters social behavior and brain oxytocin receptor density in first generation offspring

AM Yaw, JD Glass, RA Prosser, HK Caldwell - Neuroscience, 2022 - Elsevier
It is well established that the damaging effects of drugs of abuse, such as cocaine, can
extend beyond the user to their offspring. While most preclinical models of the generational …

Subtle biobehavioral effects produced by paternal cocaine exposure

CE Killinger, S Robinson, GD Stanwood - Synapse, 2012 - Wiley Online Library
Despite the increased prevalence of cocaine use and abuse in males when compared with
females, possible effects of paternal cocaine exposure on biobehavioral development have …

Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice

AM Yaw, RA Prosser, PC Jones, BJ Garcia… - Behavioural Brain …, 2019 - Elsevier
Paternal cocaine use causes phenotypic alterations in offspring behavior and associated
neural processing. In rodents, changes in first generation (F1) offspring include drug reward …

Altered reward sensitivity in female offspring of cocaine-exposed fathers

DK Fischer, RC Rice, AM Rivera, M Donohoe… - Behavioural brain …, 2017 - Elsevier
Recent rodent studies have demonstrated that parental cocaine exposure can influence
offspring behavior, supporting the idea that environmental insults can impact subsequent …

Sex-specific differences in oxytocin receptor expression and function for parental behavior

M Mitre, TM Kranz, BJ Marlin, JK Schiavo… - Gender and the …, 2017 - liebertpub.com
Parental care is among the most profound behavior expressed by humans and other
animals. Despite intense interest in understanding the biological basis of parental …

[图书][B] A rodent model of cocaine's effect on the mother infant dyad

MS McMurray - 2011 - search.proquest.com
Cocaine abuse by women is correlated with a high incidence of child neglect and abuse,
and young children prenatally exposed to cocaine show early signs of neurobehavioral …

Prenatal and gestational cocaine exposure: Effects on the oxytocin system and social behavior with implications for addiction

SK Williams, JM Johns - Pharmacology Biochemistry and Behavior, 2014 - Elsevier
Drug abuse during pregnancy is a major public health concern, with negative consequences
throughout development. Prenatal cocaine exposure (PCE) in rats produces social behavior …

Enhanced anxiety in the male offspring of sires that self‐administered cocaine

SL White, FM Vassoler, HD Schmidt… - Addiction …, 2016 - Wiley Online Library
We previously showed that paternal cocaine exposure reduced the reinforcing efficacy of
cocaine in male offspring. Here, we sought to determine whether paternal cocaine …

Reduced cocaine reinforcement in the male offspring of cocaine-experienced sires.

RC Pierce, FM Vassoler - Neuropharmacology, 2014 - nature.com
Mounting evidence suggests that parental ingestion of abused drugs influences the
physiology and behavior of future generations in the absence of prenatal exposure …

Transcriptomic effects of paternal cocaine-seeking on the reward circuitry of male offspring

N Huang, J Cui, G Fan, T Pan, K Han, K Xu… - Translational …, 2024 - nature.com
It has been previously established that paternal development of a strong incentive
motivation for cocaine can predispose offspring to develop high cocaine-seeking behavior …