Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently
induce HIV-associated neuropathic pain (HIV-NP). There is a dearth of drugs or therapeutic …

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) are the cornerstone of the
antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency …

Despite management with opioids and other pain modifying therapies, neuropathic pain
continues to reduce the quality of life and daily functioning in HIV-infected individuals …

BACKGROUND Background: Painful peripheral neuropathy continues to be a significant
clinical problem in patients (pts) with HIV infection. Preclinical studies suggest that …

Neuropathic pain associated with nucleoside reverse transcriptase inhibitors (NRTIs),
therapeutic agents for human immunodeficiency virus (HIV), responds poorly to available …

METHODS: Following a 16 patient open-label pilot proof-of-concept phase that suggested a
beneficial clinical effect of seven days of smoked cannabis, a follow-on randomized, placebo …

HIV remains a major burden to the health care system and neuropathic pain is the most
common neurological complication of HIV infection. Because current treatment strategies …

Neuropathic pain is a debilitating form of chronic pain resulting from nerve injury, disease
states, or toxic insults. Neuropathic pain is often refractory to conventional …

HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral
therapy (ART), suggesting underlying systemic and central nervous system (CNS) …

Background: Despite the successful introduction of combined antiretroviral therapy, the
prevalence of mild to moderate forms of HIV-associated neurocognitive disorders (HAND) …