Cyclophosphamide (CYP) induces an interstitial cystitis-like inflammation. The resulting
bladder dysfunction has been associated with increased release of adenosine-5 …

The aim of the present study was to investigate the relaxatory function of adenosine receptor
subtypes in rat urinary bladder, and if it is altered in the state of inflammation. The in vitro …

We characterized muscarnic and purinergic receptors and urodynamic parameters in the
bladder of cyclophosphamide (CYP)-treated rats to clarify the mechanisms involved in the …

The aim of the present study was to assess the purinoceptor functional responses of the
urinary bladder by using isolated rat urinary bladder strip preparations. ATP elicited a …

Neurogenic inflammation is linked to urinary bladder overactivity development.
Cyclophosphamide (CYP) damages all mucosal defence lines of urinary bladder and …

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a type of chronic bladder inflammation
characterized by increased voiding frequency, urgency and pelvic pain. The sensitization of …

We studied sensitization of retrogradely labeled bladder sensory neurons and plasticity of
P2X receptor function in a model of cystitis using patch-clamp techniques. Saline (control) or …

It is suggested that ATP and purinergic P2X receptors are involved in overactive bladder. In
this study, we investigated the effect of the recently developed P2X 3 and P2X 2/3 receptor …

OBJECTIVES: To investigate the effects of intravesical application of adenosine 5′-
triphosphate (ATP) on bladder activity to elucidate the role of urothelial barrier function and …

In this study, we used a well-established animal model to investigate changes in the
peptidergic and parasympathetic innervation of the bladder following chronic bladder …