The antidiuretic hormone vasopressin (AVP) regulates renal salt and water reabsorption
along the distal nephron and collecting duct system. These effects are mediated by …

The thick ascending limb of the loop of Henle (THAL) plays an important role in the
regulation of NaCl and water reabsorption. In vivo studies have shown that the free radical …

We investigated the role and mechanism of H2O2 in regulation of NaCl transport in primary
inner medullary collecting duct (IMCD) cells. IMCD cells were isolated from wild-type mice …

Differential interference contrast microscopy was used in combination with standard
electrophysiological techniques in the in vitro perfused mouse medullary thick ascending …

Nitric oxide (NO) inhibits transport in various nephron segments, and the thick ascending
limb (TAL) expresses nitric oxide synthase (NOS). However, the effects of NO on TAL …

Loop-diuretic-sensitive 86 Rb+(K+) transmembrane fluxes were determined in cells of a
mouse inner medullary collecting duct cell line (mIMCD-K2). The furosemide-sensitive (0.1 …

Arginine vasopressin (AVP) inhibits HCO3-absorption (JHCO3) in the medullary thick
ascending limb (MTAL) of the rat by increasing adenosine 3', 5'-cyclic monophosphate …

Superoxide (O2−) regulates renal function and is implicated in hypertension. O2− production
increases in response to increased ion delivery in thick ascending limbs (TALs) and macula …

The H+ and HCO3-transporters present in the medullary thick ascending limb (MTAL) of the
kidney are involved in several functions, such as transepithelial transport, defense of cell pH …

Steady-state surface levels of the apical Na/K/2Cl cotransporter NKCC2 regulate NaCl
reabsorption by epithelial cells of the renal thick ascending limb (THAL). We reported that …