[HTML][HTML] Luteal prostaglandins: mechanisms regulating luteal survival and demise in ruminants

JL Pate, CHK Hughes - animal, 2023 - Elsevier
The corpus luteum (CL) is critical for establishment and maintenance of pregnancy in all
mammals. However, the fate of the CL in ruminants is dependent on the presence of a …

Luteolysis in ruminants: past concepts, new insights, and persisting challenges

R Meidan, E Girsh, R Mamluk, N Levy… - The Life Cycle of the …, 2017 - Springer
It is well established that in ruminants, and in other species with estrous cycles, luteal
regression is stimulated by the episodic release of prostaglandin F2α (PGF2α) from the …

A review of luteolytic and luteotrophic effects of prostaglandins on the corpus luteum of pseudopregnant rabbits: some in vivo and in vitro insights

C Boiti - World Rabbit Science, 1999 - riunet.upv.es
[EN] For many years prostaglandin E2 and prostaglandin F2a have been known to exert
luteotrophic and luteolytic actions on the corpus luteum (CL) of most mammalian species …

Role of luteal prostaglandins in the control of bovine corpus luteum functions

RA Milvae - Journal of Animal Science, 1986 - academic.oup.com
Current and emerging concepts on regulation of bovine corpus luteum function by various
metabolites of arachidonic acid are reviewed. A series of experiments are presented which …

Sensitivity of Bovine Corpora Lutea to Prostaglandin F Is Dependent on Progesterone, Oxytocin, and Prostaglandins

DJ Skarzynski, K Okuda - Biology of reproduction, 1999 - academic.oup.com
Prostaglandin (PG) F2α that is released from the uterus is essential for spontaneous
luteolysis in cattle. Although PGF2α and its analogues are extensively used to synchronize …

Prostaglandin E2 functions as a luteotrophic factor in the dog

MP Kowalewski, B Fox, A Gram, A Boos… - …, 2013 - rep.bioscientifica.com
The luteal phase in dogs is governed by many poorly understood regulatory mechanisms.
Functioning of the corpus luteum (CL) is unaffected by hysterectomy. Recently, the role of …

Mechanisms of luteolysis in domestic livestock

JJ Knickerbocker, MC Wiltbank… - Domestic Animal …, 1988 - Elsevier
Secretion of progesterone from the corpus luteum is required for normal pregnancy in all
domestic animals. However, if pregnancy does not occur following estrus and mating …

Mechanisms for rescue of corpus luteum during pregnancy: gene expression in bovine corpus luteum following intrauterine pulses of prostaglandins E1 and F

JC Ochoa, F Penagaricano, GM Baez… - Biology of …, 2018 - academic.oup.com
In ruminants, uterine pulses of prostaglandin (PG) F2α characterize luteolysis, while
increased PGE2/PGE1 distinguish early pregnancy. This study evaluated intrauterine (IU) …

[HTML][HTML] Prostaglandin-mediated effects in early canine corpus luteum: in vivo effects on vascular and immune factors

MT Pereira, A Gram, R Nowaczyk, A Boos… - Reproductive …, 2019 - Elsevier
Prostaglandins (PGs) are important regulators of the early corpus luteum (CL) in the dog.
Whereas, initially, CL is gonadotropin independent, in the second half of its lifespan …

Prostaglandin F2α‐induced luteolysis involves activation of Signal transducer and activator of transcription 3 and inhibition of AKT signaling in cattle

MT Rovani, GF Ilha, BG Gasperin… - Molecular …, 2017 - Wiley Online Library
Prostaglandin F2α (PGF) induces the precipitous loss of steroidogenic capabilities and
cellular death in the corpus luteum of many species, yet the molecular mechanisms …