Pharmacological agents acting at alpha-2 adrenergic receptors are widely used in
physiology and neuroscience research. Mounting evidence of their potential utility in clinical …

The discovery of an additional duplicated alpha‐2 adrenoceptor subtype in the zebrafish
raises a pesky nomenclature issue, as well as questions about the functions of the alpha‐2 …

Brain monoamines play a key role in the regulation of behavior. Reserpine depletes
monoamines, and causes depression and hypoactivity in humans and rodents. In contrast, d …

The α2‐adrenoceptors are G‐protein‐coupled receptors that mediate many of the
physiological effects of norepinephrine and epinephrine. Mammals have three subtypes of …

CGS 7525A, a new tetracyclic compound, was evaluated for alpha 2 adrenoceptor
antagonism in receptor binding assays and in behavioral and electrophysiological tests. 3 H …

Abstract Modafinil (2-((diphenylmethyl) sulfinyl) acetamide), a selective dopamine and
norepinephrine transporter inhibitor, is most commonly prescribed for narcolepsy but has …

The photoaffinity probe 125I‐APDQ has been used to characterize α1‐receptor peptides in
the cod and rat brains. In the cod brain a major specific peptide of Mt= 68,000 could be …

Alpha2-adrenergic receptors (α2-adrenoceptors) mediate various physiological actions of
endogenous catecholamines in the central and peripheral nervous systems being involved …

Deficits in social communication and interaction are core clinical symptoms characterizing
multiple neuropsychiatric conditions, including autism spectrum disorder (ASD) and …

582 trast to the estimated 7 million veterinary patients that receive an alpha-2 agonist as a
sedative-analgesic or anesthetic adjunctive agent each year. This difference in the choice …