Screening for colorectal cancer Page 1 THE LANCET 356 Vol 349 • February 1, 1997 from
colorectal cancer. This calls into question Lieberman and Sleisenger’s3 accompanying …

Ponders whether total mesorectal excision should be the routine operation for rectal cancer.
The mechanisms by which the medical community changes beliefs about surgical …

Questions the histogenesis of colonic adenomas or whether colon adenomatous polyps
grow inward. The outward migration of coloncytes towards the lumen of normal crypts; …

315: 696. defendable, although commonly misunderstood and misapplied, especially by
workers who are accustomed to publishing in journals that do not educate their authors by …

As we move into the era of stratified medicine, how should the Article by Timothy Maughan
and colleagues1 in The Lancet shape treatment of patients with metastatic colorectal …

Summarizes events in the biology, diagnosis, therapy and surveillance of patients with
colorectal carcinoma in the past twenty years to 1993. Transformation in the organ system …

Examination of western demographic data show that over the past 25 years there has been
an increase in individuals and cohorts older than 75 years. 1 Furthermore, this concentration …

Cell proliferation and cancer Cell division in the gastrointestinal tract is the largest and
second-fastest cell-renewal system in the body. Stem cells at the base of each crypt give rise …

Adjuvant chemotherapy with fluorouracil and lev amisole for 1 year after the surgical
resection of nodepositive (stage III) colon cancer was established in 1990. 1 Subsequent …