Germline pathogenic variants in patients with early-onset neuroendocrine neoplasms

RP Riechelmann, MDS Donadio… - Endocrine-Related …, 2023 - erc.bioscientifica.com
Neuroendocrine neoplasms (NENs) are a rare group of cancers with heterogeneous
behaviour and mostly of unknown aetiology. Excluding some infrequent hereditary cancer …

Inherited neuroendocrine neoplasms

O Mete, F Hannah-Shmouni, R Kim… - The Spectrum of …, 2021 - Springer
Inherited neuroendocrine neoplasms (NENs) represent a heterogeneous group of disorders
that often present with subtle clinical or biochemical features. The well-recognized entities …

Clinical implications of pathogenic germline variants in small intestine neuroendocrine tumors (SI-NETs)

K Perez, MH Kulke, A Chittenden, C Ukaegbu… - JCO Precision …, 2021 - ascopubs.org
PURPOSE An inherited basis for presumed sporadic neuroendocrine tumor (NET) has been
suggested by evidence of familial clustering of NET and a higher incidence of second …

Genomics of high-grade neuroendocrine neoplasms: well-differentiated neuroendocrine tumor with high-grade features (G3 NET) and neuroendocrine carcinomas …

S Uccella, S La Rosa, J Metovic, D Marchiori… - Endocrine …, 2021 - Springer
High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …

GEP-NETS UPDATE: Genetics of neuroendocrine tumors

J Crona, B Skogseid - European journal of endocrinology, 2016 - academic.oup.com
Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms, arising from
neuroendocrine cells that are dispersed throughout the body. Around 20% of NETs occur in …

[HTML][HTML] Genomic dissection of gastrointestinal and lung neuroendocrine neoplasm

H Wang, L Sun, H Bao, A Wang, P Zhang… - Chinese Journal of …, 2019 - ncbi.nlm.nih.gov
Objective Neuroendocrine neoplasms (NENs) are relatively rare and heterogeneous
malignancies with two major subtypes: low-grade neuroendocrine tumor (NET) and high …

[HTML][HTML] Neuroendocrine neoplasms of lung, pancreas and gut: a morphology-based comparison

A Kasajima, G Klöppel - Endocrine-Related Cancer, 2020 - erc.bioscientifica.com
The bronchopulmonary (BP) and gastroenteropancreatic (GEP) organ systems harbor the
majority of the neuroendocrine neoplasms (NENs) of the body, comprising 20 and 70% of all …

Family history of cancer and associated risk of developing neuroendocrine tumors: a case-control study

MM Hassan, A Phan, D Li, CG Dagohoy, C Leary… - … Biomarkers & Prevention, 2008 - AACR
Background: Carcinoids are rare neuroendocrine tumors (NET). Familial clusterings of NETs
are rarely reported, except for a small proportion associated with multiple endocrine …

Genetic associations with neuroendocrine tumor risk: results from a genome-wide association study

Y Du, M Ter-Minassian, L Brais, N Brooks… - Endocr Relat …, 2016 - erc.bioscientifica.com
The etiology of neuroendocrine tumors remains poorly defined. Although neuroendocrine
tumors are in some cases associated with inherited genetic syndromes, such syndromes are …

Lung and digestive neuroendocrine neoplasms. From WHO classification to biomarker screening: Which perspectives?

JY Scoazec - Annales d'Endocrinologie, 2019 - Elsevier
The recent classifications of lung and digestive neuroendocrine neoplasms (NENs) make a
fundamental distinction between well-and poorly-differentiated neoplasms. Well …