Somatic and germline mutations in NETs: Implications for their diagnosis and management

M Minnetti, A Grossman - Best Practice & Research Clinical Endocrinology …, 2016 - Elsevier
It is now understood that specific somatic and germline mutations may lead to the
development of the neuroendocrine tumours (NETs). NETs usually occur as sporadic …

Genetics of neuroendocrine and carcinoid tumours.

PD Leotlela, A Jauch, H Holtgreve-Grez… - Endocrine-related …, 2003 - erc.bioscientifica.com
Neuroendocrine tumours (NETs) originate in tissues that contain cells derived from the
embryonic neural crest, neuroectoderm and endoderm. Thus, NETs occur at many sites in …

[HTML][HTML] Inherited syndromes involving pancreatic neuroendocrine tumors

JL Geurts - Journal of Gastrointestinal Oncology, 2020 - ncbi.nlm.nih.gov
Inherited syndromes are important to recognize in the setting of a pancreatic
neuroendocrine tumor (PNET) as there are significant implications for the patient's medical …

Under-representation of racial groups in genomics studies of gastroenteropancreatic neuroendocrine neoplasms

BR Herring, A Bonner, RE Guenter, S Vickers… - Cancer Research …, 2022 - AACR
Not all populations are poised to benefit from advancing genomics in
gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN), as genomics have focused …

Pancreatic neuroendocrine neoplasms: updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classification

H Ishida, AK Lam - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (PanNENs) are the neuroendocrine neoplasms with
greatest rate of increase in incidence. Approximately 10% of PanNENs arise as inherited …

Germline CDKN1B variant type and site are associated with phenotype in MEN4

R Halperin, L Arnon, S Nasirov… - Endocrine-Related …, 2023 - erc.bioscientifica.com
Multiple endocrine neoplasia 4 (MEN4) is a rare multiglandular endocrine neoplasia
syndrome clinically hallmarked by primary hyperparathyroidism (PHPT), pituitary adenoma …

Neuroendocrine tumors in children and young adults: rare or not so rare

ME Sarvida, MS O'Dorisio - Endocrinology and Metabolism …, 2011 - endo.theclinics.com
Endocrine tumors are neoplasms arising from endocrine organs, regardless of whether the
tumor secretes hormones, and tumors producing or secreting hormones, regardless of the …

Genetics of pancreatic neuroendocrine tumors

C Mohindroo, F McAllister… - Hematology …, 2022 - hemonc.theclinics.com
Pancreatic neuroendocrine tumors (pNETs) are characterized as a rare disease with an
incidence of less than 1 in 100,000 individuals per year, and accounts for 1% to 2% of all …

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

B Lawrence, C Blenkiron, K Parker, P Tsai… - NPJ genomic …, 2018 - nature.com
Pancreatic neuroendocrine tumors (pNETs) are uncommon cancers arising from pancreatic
islet cells. Here we report the analysis of gene mutation, copy number, and RNA expression …

Incidence and survival outcomes in patients with lung neuroendocrine neoplasms in the United States

S Shah, R Gosain, A Groman, R Gosain, A Dasari… - Cancers, 2021 - mdpi.com
Simple Summary Neuroendocrine tumors are a rare group of neoplasms characterized by
strikingly heterogeneous pathological features and clinical behavior. The incidence and …