A differential diagnosis of inherited endocrine tumors and their tumor counterparts

SPA Toledo, DM Lourenço Jr, RA Toledo - Clinics, 2013 - SciELO Brasil
Inherited endocrine tumors have been increasingly recognized in clinical practice, although
some difficulties still exist in differentiating these conditions from their sporadic endocrine …

[HTML][HTML] Histopathological, immunohistochemical, genetic and molecular markers of neuroendocrine neoplasms

G Kyriakopoulos, V Mavroeidi, E Chatzellis… - Annals of …, 2018 - ncbi.nlm.nih.gov
Neuroendocrine neoplasms (NENs) arise from cells of the neuroendocrine system located in
many sites amongst which most common are the gastrointestinal (GI) system and the lung …

Molecular Classification of Gastrointestinal and Pancreatic Neuroendocrine Neoplasms: Are We Ready for That?

S Uccella - Endocrine Pathology, 2024 - Springer
In the last two decades, the increasing availability of technologies for molecular analyses
has allowed an insight in the genomic alterations of neuroendocrine neoplasms (NEN) of …

Endocrine paraneoplastic syndromes in patients with neuroendocrine neoplasms

K Daskalakis, E Chatzelis, M Tsoli… - Endocrine, 2019 - Springer
Objective Our aim was to assess the prevalence of endocrine paraneoplastic syndromes
(EPNS) in neuroendocrine neoplasms (NENs) and estimate its impact on patient outcomes …

Genetic predisposition to endocrine tumors: Diagnosis, surveillance and challenges in care

EJ Petr, T Else - Seminars in oncology, 2016 - Elsevier
Endocrine tumor syndromes, eg, multiple endocrine neoplasia types 1 and 2, were among
the first recognized hereditary predisposition syndromes to tumor development. Over time …

Genetics and molecular pathology of neuroendocrine gastrointestinal and pancreatic tumors (gastroenteropancreatic neuroendocrine tumors)

K Öberg - Current Opinion in Endocrinology, Diabetes and …, 2009 - journals.lww.com
Molecular profiling of GEP-NETs demonstrates that pancreatic endocrine tumors and
gastrointestinal neuroendocrine tumors (carcinoids) display different genetic changes and …

Neuroendocrine neoplasms: two families with distinct features unified in one classification (German version)

G Klöppel - Der Pathologe, 2019 - Springer
All neuroendocrine neoplasms (NENs) are characterized by the expression of
synaptophysin and chromogranin A (or B). Yet, they are not a homogeneous group of …

The genomic landscape of small intestine neuroendocrine tumors

MS Banck, R Kanwar, AA Kulkarni… - The Journal of …, 2013 - Am Soc Clin Investig
Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the
small bowel. Several clinical trials target PI3K/Akt/mTOR signaling; however, it is unknown …

Recent advances and current controversies in lung neuroendocrine neoplasms✰

J Metovic, F Bianchi, G Rossi, M Barella… - Seminars in Diagnostic …, 2021 - Elsevier
In the lung, neuroendocrine tumors (NETs), namely typical and atypical carcinoids, and
neuroendocrine carcinomas (NECs), grouping small cell carcinoma (SCLC) and large cell …

Genomic Landscape of Pancreatic Neuroendocrine Tumors and Implications for Clinical Practice

A De Jesus-Acosta, C Mohindroo - JCO Precision Oncology, 2024 - ascopubs.org
Pancreatic neuroendocrine tumors (pNETs) are the second most prevalent neoplasms of the
pancreas with variable prognosis and clinical course. Our knowledge of the genetic …