EtMIC3 and its receptors BAG1 and ENDOUL are essential for site-specific invasion of Eimeria tenella in chickens

W Li, M Wang, Y Chen, C Chen, X Liu, X Sun, C Jing… - Veterinary …, 2020 - Springer
Avian coccidian parasites exhibit a high degree of site specificity in different Eimeria
species. Although the underlying mechanism is unclear, an increasing body of evidence …

Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cells

W Chen, C Ma, G Li, Z Jia, X Yang, X Pan, D Ma - Veterinary Research, 2021 - Springer
Avian coccidiosis caused by Eimeria leads to huge economic losses on the global poultry
industry. In this study, microneme adhesive repeat regions (MARR) bc1 of E. tenella …

[HTML][HTML] Identification and characterization of the receptors of a microneme adhesive repeat domain of Eimeria maxima microneme protein 3 in chicken intestine …

Y Zhang, M Lu, J Huang, X Tian, M Liang, M Wang… - Poultry Science, 2024 - Elsevier
Eimeria maxima microneme protein 3 (EmMIC3) is pivotal in the initial recognition and
attachment of E. maxima sporozoites to host cells. EmMIC3 comprises 5 tandem Type I …

Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

L Sun, C Li, N Zhao, B Wang, H Li, H Wang… - Microbial …, 2024 - Elsevier
The five epidermal growth factor-like domains (EGF) of Eimeria tenella microneme protein 8
(EtMIC8)(EtMIC8-EGF) plays a vital role in host cell attachment and invasion. These …

Characterization of Monoclonal Antibodies that Recognize the Eimeria tenella Microneme Protein MIC2

K Sasai, RH Fetterer, H Lillehoj… - Journal of …, 2008 - meridian.allenpress.com
The apicomplexan pathogens of Eimeria tenella cause coccidiosis, an intestinal disease of
chickens that has a major economic impact on the poultry industry. Members of Apicomplexa …

[HTML][HTML] Eimeria tenella: specific EtAMA1-binding peptides inhibit sporozoite entry into host cells

D Ma, Y Huang, C Ma, L Zhang, J Wang, D Wang, J Li… - Poultry Science, 2019 - Elsevier
Avian coccidiosis caused by Eimeria inflicts high economic losses to the poultry industry.
Application of drugs and live vaccines presents particular challenges in pathogen resistance …

The microneme adhesive repeat domain of MIC3 protein determined the site specificity of Eimeria acervulina, Eimeria maxima, and Eimeria mitis

Y Zhang, M Lu, Z Zhang, X Huang, J Huang… - Frontiers in …, 2023 - frontiersin.org
Understanding the determinants of host and tissue tropisms among parasites of veterinary
and medical importance has long posed a substantial challenge. Among the seven species …

[HTML][HTML] Molecular characterization and protective efficacy of the microneme 2 protein from Eimeria tenella

M Yan, X Cui, Q Zhao, S Zhu, B Huang, L Wang… - Parasite, 2018 - ncbi.nlm.nih.gov
Microneme proteins play an important role in the adherence of apicomplexan parasites to
host cells during the invasion process. In this study, the microneme 2 protein from the …

Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8)

N Zhao, S Ming, L Sun, B Wang, H Li… - Microbiology …, 2021 - Am Soc Microbiol
ABSTRACT Microneme proteins (MICs) of Eimeria tenella play key roles in motility,
migration, attachment, and invasion processes. More than 20 apicomplexan parasite's MICs …

Partial protective of chickens against Eimeria tenella challenge with recombinant EtMIC-1 antigen

NS Qi, YY Wang, SQ Liao, CY Wu, MN Lv, J Li… - Parasitology …, 2013 - Springer
Eimeria tenella microneme protein 1 (EtMIC-1) is highly conserved with TgMIC-2, which is
involved in parasite binding specifically to host cells. Little is known about the immune …