This chapter focuses on drug-drug interactions and their effect on the market place.
Terfenadine was introduced into the marketplace as the first nonsedating histamine-1 …

The number of drugs available to treat patient illness is steadily increasing as drug
development benefits from advances in molecular biology and from increasing automation …

Following the recent withdrawal of several prominent drugs from US and European markets
because of detrimental drug-drug interactions, metabolic drug interactions have received …

Introduction Antihistamines are among the most fre-quently prescribed drugs in the world.
Because the clinical use of older antihistamines (eg, diphenhydramine, hydroxyzine) was …

Focuses on the role of the US Food and Drug Administration (FDA) in determining the
interaction problems of drugs. Reference to a drug interaction case concerning the allergy …

Interactions between drugs were first recognized over 100 years ago. A drug interaction is
said to occur when the response of a patient to a drug is changed by the presence of …

Drug Drug Interactions is a comprehensive review of the scientific and regulatory
perspectives of drug drug interactions from the point-of-view of academia, industry, and …

The drug interactions appendix in the current issue of the British National Formulary lists
about 3000 interactions or groups of interactions (the number of individual interactions is …