Pervasive transcription is a widespread phenomenon leading to the production of a plethora
of non‐coding RNA s (nc RNA s) without apparent function. Pervasive transcription poses a …

Pervasive transcription is widespread and needs to be controlled in order to avoid
interference with gene expression. In Saccharomyces cerevisiae, the highly conserved …

Transcription termination is essential to generate functional RNAs and to prevent disruptive
polymerase collisions resulting from concurrent transcription. The yeast Sen1p helicase is …

Transcriptome studies on eukaryotic cells have revealed an unexpected abundance and
diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which …

Many non-coding transcripts (ncRNA) generated by RNA polymerase II in S. cerevisiae are
terminated by the Nrd1-Nab3-Sen1 complex. However, Sen1 helicase levels are …

Abstract RNA polymerase II (Pol II) in Saccharomyces cerevisiae can terminate transcription
via several pathways. To study how a mechanism is chosen, we analyzed recruitment of …

In Saccharomyces cerevisiae, transcription termination at protein-coding genes is coupled to
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …

The essential helicase-like protein Sen1 mediates termination of RNA Polymerase II (Pol II)
transcription at snoRNAs and other noncoding RNAs in yeast. A mutation in the Pol II …

In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA
polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and …

Sen1 is an essential helicase for factor-dependent transcription termination in
Saccharomyces cerevisiae, whose molecular-motor mechanism has not been well …