[PDF][PDF] Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters

H Qiu, C Hu, AG Hinnebusch - Molecular cell, 2009 - cell.com
Cyclin-dependent kinase BUR1/BUR2 appears to be the yeast ortholog of P-TEFb, which
phosphorylates Ser2 of the RNA Pol II CTD, but the importance of BUR1/BUR2 in CTD …

Terminating the transcript: breaking up is hard to do

E Rosonina, S Kaneko, JL Manley - Genes & development, 2006 - genesdev.cshlp.org
Transcription termination occurs when a transcribing RNA polymerase releases the DNA
template and the nascent RNA. Termination is required for preventing the inappropriate …

[PDF][PDF] Distinct pathways for snoRNA and mRNA termination

M Kim, L Vasiljeva, OJ Rando, A Zhelkovsky, C Moore… - Molecular cell, 2006 - cell.com
Transcription termination at mRNA genes is linked to polyadenylation. Cleavage at the poly
(A) site generates an entry point for the Rat1/Xrn2 exonuclease, which degrades the …

The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression

M Duval, C Yague-Sanz, TW Turowski… - Nature …, 2023 - nature.com
Transcription by RNA polymerase I (RNAPI) represents most of the transcriptional activity in
eukaryotic cells and is associated with the production of mature ribosomal RNA (rRNA). As …

RNA polymerase II CTD interactome with 3′ processing and termination factors in fission yeast and its impact on phosphate homeostasis

AM Sanchez, S Shuman… - Proceedings of the …, 2018 - National Acad Sciences
The carboxy-terminal domain (CTD) code encrypted within the Y1S2P3T4S5P6S7 heptad
repeats of RNA polymerase II (Pol2) is deeply rooted in eukaryal biology. Key steps to …

[PDF][PDF] Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly (dT) termination signals

M Girbig, J Xie, H Grötsch, D Libri, O Porrua, CW Müller - Cell Reports, 2022 - cell.com
RNA polymerase (Pol) III is specialized to transcribe short, abundant RNAs, for which it
terminates transcription on polythymine (dT) stretches on the non-template (NT) strand …

Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II …

EJ Steinmetz, DA Brow - Proceedings of the National …, 1998 - National Acad Sciences
Nrd1 is an essential yeast protein of unknown function that has an RNA recognition motif
(RRM) in its carboxyl half and a putative RNA polymerase II-binding domain, the CTD …

A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast

N Leporé, DLJ Lafontaine - PLoS One, 2011 - journals.plos.org
Ribogenesis is a multistep error-prone process that is actively monitored by quality control
mechanisms. How ribosomal RNA synthesis, pre-rRNA processing and nucleolar …

Role of Ser7 phosphorylation of the CTD during transcription of snRNA genes

S Egloff - RNA biology, 2012 - Taylor & Francis
The largest subunit of RNA polymerase (pol) II, Rpb1, contains an unusual carboxyl-terminal
domain (CTD) composed of consecutive repeats of the sequence Tyr-Ser-Pro-Thr-Ser-Pro …

Ssu72 protein mediates both poly (A)-coupled and poly (A)-independent termination of RNA polymerase II transcription

EJ Steinmetz, DA Brow - Molecular and cellular biology, 2003 - Taylor & Francis
Termination of transcription by RNA polymerase II (Pol II) is a poorly understood yet
essential step in eukaryotic gene expression. Termination of pre-mRNA synthesis is coupled …