Effect of growth hormone on insulin signaling
Growth hormone (GH) is a pleiotropic hormone that coordinates an array of physiological
processes, including effects on bone, muscle, and fat, ultimately resulting in growth …
processes, including effects on bone, muscle, and fat, ultimately resulting in growth …
The effects of growth hormone on adipose tissue: old observations, new mechanisms
The ability of growth hormone (GH) to induce adipose tissue lipolysis has been known for
over five decades; however, the molecular mechanisms that mediate this effect and the …
over five decades; however, the molecular mechanisms that mediate this effect and the …
Growth hormone acts along the PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes
VM Sharma, ET Vestergaard… - American Journal …, 2019 - journals.physiology.org
The lipolytic effects of growth hormone (GH) have been known for half a century and play an
important physiological role for substrate metabolism during fasting. In addition, sustained …
important physiological role for substrate metabolism during fasting. In addition, sustained …
Biological effects of growth hormone on carbohydrate and lipid metabolism
This review will summarize the metabolic effects of growth hormone (GH) on the adipose
tissue, liver, and skeletal muscle with focus on lipid and carbohydrate metabolism. The …
tissue, liver, and skeletal muscle with focus on lipid and carbohydrate metabolism. The …
Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure
S Nielsen, N Møller, JS Christiansen… - Diabetes, 2001 - Am Diabetes Assoc
Stimulation of lipolysis and the induction of resistance to insulin's actions on glucose
metabolism are well-recognized effects of growth hormone (GH). To evaluate whether these …
metabolism are well-recognized effects of growth hormone (GH). To evaluate whether these …
Growth Hormone Signaling in Vivo in Human Muscle and Adipose Tissue: Impact of Insulin, Substrate Background, and Growth Hormone Receptor Blockade
Context: GH induces insulin resistance in muscle and fat, and in vitro data indicate that this
may involve cross-talk between the signaling pathways of the two hormones. Objective: Our …
may involve cross-talk between the signaling pathways of the two hormones. Objective: Our …
The intricate role of growth hormone in metabolism
A Vijayakumar, S Yakar, D LeRoith - Frontiers in endocrinology, 2011 - frontiersin.org
Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …
Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
N Møller, JOL Jørgensen - Endocrine reviews, 2009 - academic.oup.com
In evolutionary terms, GH and intracellular STAT 5 signaling is a very old regulatory system.
Whereas insulin dominates periprandially, GH may be viewed as the primary anabolic …
Whereas insulin dominates periprandially, GH may be viewed as the primary anabolic …
[PDF][PDF] Impact of growth hormone on regulation of adipose tissue
KM Troike, BE Henry, EA Jensen, JA Young… - Compr …, 2017 - researchgate.net
Increasing prevalence of obesity and obesity-related conditions worldwide has necessitated
a more thorough understanding of adipose tissue (AT) and expanded the scope of research …
a more thorough understanding of adipose tissue (AT) and expanded the scope of research …
Growth hormone and adipose tissue: beyond the adipocyte
DE Berryman, EO List, L Sackmann-Sala… - Growth Hormone & IGF …, 2011 - Elsevier
The last two decades have seen resurgence in research focused on adipose tissue. In part,
the enhanced interest stems from an alarming increase in obesity rates worldwide. However …
the enhanced interest stems from an alarming increase in obesity rates worldwide. However …
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