Nutrient sensing plays an important role in ensuring that appropriate digestive or hormonal
responses are elicited following the ingestion of fuel substrates. Mechanisms of nutrient …

The release of gut hormones involved in the control of food intake is dependent on the acute
nutritional status of the body, suggesting that chemosensory mechanisms are involved in the …

The chemical environment of the intestinal lumen and the presence of nutrients in the gut
result in the secretion of regulatory peptides and in the discharge of intestinal sensory …

The sense of taste is positioned at the forefront when it comes to the interaction of our body
with foodborne chemicals. However, the role of our taste system, and in particular its …

Many of the receptors and downstream signaling elements involved in taste detection and
transduction are also expressed in enteroendocrine cells where they underlie the …

The discovery of taste and nutrient receptors (chemosensors) in the gut has led to intensive
research on their functions. Whereas oral sugar, fat, and umami taste receptors stimulate …

The primary sensors in the gut are endocrine cells. They release peptides and amines that
stimulate intrinsic and extrinsic neural pathways affecting gastrointestinal motor and …

In the last 15 years, advancements in molecular biology have unraveled the proteins that
function as taste receptors. There are at least five taste qualities that are consciously …

Sensing nutrients within the gastrointestinal tract engages the enteroendocrine cell system
to signal within the mucosa, to intrinsic and extrinsic nerve pathways, and the circulation …

Recent progress in unravelling the nutrient-sensing mechanisms in the taste buds of the
tongue has triggered studies on the existence and role of chemosensory cells in the gut …