Air pollution, stress, and allostatic load: linking systemic and central nervous system impacts

EM Thomson - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Air pollution is a risk factor for cardiovascular and respiratory morbidity and mortality. A
growing literature also links exposure to diverse air pollutants (eg, nanoparticles, particulate …

The adverse effects of air pollution on the nervous system

S Genc, Z Zadeoglulari, SH Fuss… - Journal of toxicology, 2012 - Wiley Online Library
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …

Mapping acute systemic effects of inhaled particulate matter and ozone: multiorgan gene expression and glucocorticoid activity

EM Thomson, D Vladisavljevic… - toxicological …, 2013 - academic.oup.com
Recent epidemiological studies have demonstrated associations between air pollution and
adverse effects that extend beyond respiratory and cardiovascular disease, including low …

Air pollution, depressive and anxiety disorders, and brain effects: A systematic review

CG Zundel, P Ryan, C Brokamp, A Heeter, Y Huang… - Neurotoxicology, 2022 - Elsevier
Accumulating data suggest that air pollution increases the risk of internalizing
psychopathology, including anxiety and depressive disorders. Moreover, the link between …

Stretching the stress boundary: Linking air pollution health effects to a neurohormonal stress response

UP Kodavanti - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Inhaled pollutants produce effects in virtually all organ systems in our body and have been
linked to chronic diseases including hypertension, atherosclerosis, Alzheimer's and …

Air pollution: mechanisms of neuroinflammation and CNS disease

ML Block, L Calderón-Garcidueñas - Trends in neurosciences, 2009 - cell.com
Air pollution has been implicated as a chronic source of neuroinflammation and reactive
oxygen species (ROS) that produce neuropathology and central nervous system (CNS) …

Particulate air pollution and risk of neuropsychiatric outcomes. What we breathe, swallow, and put on our skin matters

L Calderón-Garcidueñas, EW Stommel… - International Journal of …, 2021 - mdpi.com
We appraise newly accumulated evidence of the impact of particle pollution on the brain, the
portals of entry, the neural damage mechanisms, and ultimately the neurological and …

Air pollution–related neurotoxicity across the life span

DA Cory-Slechta, A Merrill… - Annual review of …, 2023 - annualreviews.org
Air pollution is a complex mixture of gases and particulate matter, with adsorbed organic and
inorganic contaminants, to which exposure is lifelong. Epidemiological studies increasingly …

Outdoor ambient air pollution and neurodegenerative diseases: the neuroinflammation hypothesis

RL Jayaraj, EA Rodriguez, Y Wang… - Current environmental …, 2017 - Springer
Abstract Purpose of Review Accumulating research indicates that ambient outdoor air
pollution impacts the brain and may affect neurodegenerative diseases, yet the potential …

[HTML][HTML] Stress hormones as potential mediators of air pollutant effects on the brain: rapid induction of glucocorticoid-responsive genes

EM Thomson, A Filiatreault, J Guénette - Environmental research, 2019 - Elsevier
Air pollution is associated with adverse effects on brain health including cognitive decline,
dementia, anxiety, depression, and suicide. While toxicological studies have demonstrated …