In patients with localized scleroderma (LoS), facial deformity induced by subcutaneous
atrophy greatly reduces life quality. Autologous fat grafting (AFG) is used for volume …

Background Adipose-derived stem cells (ADSCs) are emerging as an alternative stem cell
source for cell-based therapies. Recent data suggest that autologous ADSC-enriched …

Background: Although autologous fat grafting is a feasible surgical technique to improve
facial deformity in patients with localized scleroderma, its success is limited by the low graft …

Background The use of stem cells, including mesenchymal stem cells (MSCs), for
regenerative medicine is gaining interest for the clinical benefits so far obtained in patients …

Adipose-derived stem cells (ADSCs) residing in the stromal vascular fraction (SVF) of white
adipose tissue are recently emerging as an alternative tool for stem cell-based therapy in …

Fat is an ideal tissue as an autologous substitute with which tissue deficiencies can be
treated. It is available in easily accessible subcutaneous depots but also can be molded to …

Background Numerous methods have been proposed to enhance the survival of fat grafts,
but no definitive treatment is available. Stromal vascular fraction (SVF)-assisted cell therapy …

The present study was designed to evaluate the clinical outcome of cell-based therapy with
cultured adipose-derived stromal cells (ASCs) for the treatment of cutaneous manifestations …

Objectives The aim of this study was to evaluate the safety and efficacy of the use of FG-
SVFs in face rejuvenation for esthetic improvement. Methods 33 female patients affected by …

Pathological scarring and scleroderma, which are the most common conditions of skin
fibrosis, pathologically manifest as fibroblast proliferation and extracellular matrix (ECM) …