Aims The purpose of this study was to determine the feasibility of a new positron emission
tomography (PET) imaging approach using an 18F-labelled αvβ3 integrin antagonist (18F …

Graft arteriopathy (GA), characterized by diffuse concentric narrowing of coronary arteries, is
the major cause of late graft failure in cardiac transplantation. αvβ3 Integrin is up‐regulated …

Recent evidence suggests that αvβ3 integrin is a critical molecule in several processes
involved in atherosclerosis progression and in restenosis, eg, smooth muscle cell (SMC) …

Purpose Molecular imaging of α v β 3 integrin has exhibited real potential to guide the
appropriate use of anti-angiogenic therapies. However, an incomplete understanding of the …

Objective—Inflammation plays a key role in the development of vascular diseases.
Monocytes and macrophages express αvβ3 integrin. We used an αv integrin-specific tracer …

Increased expression of fibroblast-activating protein (FAP) in fibrous caps may contribute to
progression of atherosclerotic plaques. Methods: Forty-one patients who underwent 68Ga …

Objective Mural inflammation has been shown to contribute to the development of plaque,
with the αVβ3 integrin highly expressed in atherosclerotic plaques. We herein examined …

(1) This study compared [68Ga] PentixaFor uptake in active arterial segments with
corresponding [18F] FDG arterial uptake as well as the relationship with cardiac [68Ga] …

Despite in vivo mapping of integrin αvβ3 expression being thoroughly investigated in recent
years, its clinical value is still not well defined. For imaging of angiogenesis, the integrin …

Objectives—The α2β1 integrin serves as a collagen or collagen/laminin receptor on many
cell types, including endothelial cells and platelets. Many studies indicate that the α2β1 …