Effect of Selective or Combined Inhibition of Integrins αIIbβ3 and αvβ3 on Thrombosis and Neointima After Oversized Porcine Coronary Angioplasty
Background—Thrombosis and neointima formation limit the efficacy of coronary angioplasty
(PTCA). Clinical trials have implicated the adhesion molecules integrin αIIbβ3 and integrin …
(PTCA). Clinical trials have implicated the adhesion molecules integrin αIIbβ3 and integrin …
Molecular imaging of αvβ3 integrin expression in atherosclerotic plaques with a mimetic of RGD peptide grafted to Gd-DTPA
C Burtea, S Laurent, O Murariu, D Rattat… - Cardiovascular …, 2008 - academic.oup.com
Aims The integrin αvβ3 is highly expressed in atherosclerotic plaques by medial and intimal
smooth muscle cells and by endothelial cells of angiogenic microvessels. In this study, we …
smooth muscle cells and by endothelial cells of angiogenic microvessels. In this study, we …
In vivo molecular imaging of angiogenesis, targeting αvβ3 integrin expression, in a patient after acute myocardial infarction
MR Makowski, U Ebersberger, S Nekolla… - European heart …, 2008 - academic.oup.com
A 35-year-old Caucasian male presented with chest pain and nausea in the emergency
room. The initial ECG displayed sinus-rhythm with ST elevation in I, aVL, V1–5, ST …
room. The initial ECG displayed sinus-rhythm with ST elevation in I, aVL, V1–5, ST …
PET of αvβ3-integrin and αvβ5-integrin expression with 18F-fluciclatide for assessment of response to targeted therapy: ready for prime time?
AJ Beer, M Schwaiger - Journal of Nuclear Medicine, 2011 - Soc Nuclear Med
Angiogenesis, the formation of new blood vessels, is one of the hallmarks of cancer and a
key process in the growth of solid tumors (1). Therefore, this process could be targeted for …
key process in the growth of solid tumors (1). Therefore, this process could be targeted for …
α8β1 Integrin expression in the rat carotid artery: involvement in smooth muscle cell migration and neointima formation
R Zargham, G Thibault - Cardiovascular research, 2005 - academic.oup.com
Objective: Migration of vascular smooth muscle cells (VSMCs) from the tunica media to the
intima is a key event in neointima formation after coronary artery angioplasty. The central …
intima is a key event in neointima formation after coronary artery angioplasty. The central …
There is a world beyond αvβ3-integrin: multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography
K Steiger, NG Quigley, T Groll, F Richter, MA Zierke… - EJNMMI research, 2021 - Springer
Background In the context of nuclear medicine and theranostics, integrin-related research
and development was, for most of the time, focused predominantly on'RGD peptides' and the …
and development was, for most of the time, focused predominantly on'RGD peptides' and the …
[HTML][HTML] Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
OBJECTIVES: Atherosclerosis is recognised as an inflammatory disease, and new
diagnostic tools are warranted to evaluate plaque inflammatory activity and risk of …
diagnostic tools are warranted to evaluate plaque inflammatory activity and risk of …
A Monoclonal Antibody Against αVβ3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs
LA Maile, WH Busby, TC Nichols… - Science translational …, 2010 - science.org
Atherosclerotic lesions develop and progress more rapidly in diabetic patients than in
nondiabetic individuals. This may be caused by accelerated lesion formation in the high …
nondiabetic individuals. This may be caused by accelerated lesion formation in the high …
Beta3 integrin--a promiscuous integrin involved in vascular pathology.
JP Veinot, S Srivatsa, P Carlson - The Canadian journal of …, 1999 - europepmc.org
Beta3 integrin--a promiscuous integrin involved in vascular pathology. - Abstract - Europe PMC
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p
A Broisat, LM Riou, V Ardisson, D Boturyn… - European journal of …, 2007 - Springer
Purpose VCAM-1 plays a major role in the chronic inflammatory processes present in
vulnerable atherosclerotic plaques. The residues 75–84 (B2702-p) and 84–75/75–84 …
vulnerable atherosclerotic plaques. The residues 75–84 (B2702-p) and 84–75/75–84 …