Effects of saffron (Crocus sativus L.) on cognitive function. A systematic review of RCTs

KI Avgerinos, C Vrysis, N Chaitidis, K Kolotsiou… - Neurological …, 2020 - Springer
Introduction Improvement of cognitive function may be desirable for healthy individuals and
clinically beneficial for those with cognitive impairment such as from Alzheimer's disease …

[HTML][HTML] Saffron for mild cognitive impairment and dementia: a systematic review and meta-analysis of randomised clinical trials

Z Ayati, G Yang, MH Ayati, SA Emami… - … medicine and therapies, 2020 - Springer
Abstract Background Saffron (stigma of Crocus sativus L.) from Iridaceae family is a well-
known traditional herbal medicine that has been used for hundreds of years to treat several …

[HTML][HTML] Crocus sativus L.(Saffron) in Alzheimer's disease treatment: Bioactive effects on cognitive impairment

G D'Onofrio, SM Nabavi, D Sancarlo… - Current …, 2021 - ncbi.nlm.nih.gov
Crocus sativus L.(saffron) appears to own neuroprotective effects on cognitive impairment in
patients with Alzheimer's disease (AD). The purpose of this work is to review evidence and …

New horizons for the study of saffron (Crocus sativus L.) and its active ingredients in the management of neurological and psychiatric disorders: A systematic review of …

S Han, Y Cao, X Wu, J Xu, Z Nie… - Phytotherapy Research, 2024 - Wiley Online Library
Saffron (Crocus sativus), as an herbal medicine, has been extensively investigated for
treating neurological and psychiatric disorders. This systematic review aimed to assess the …

Comparing the efficacy and safety of Crocus sativus L. with memantine in patients with moderate to severe Alzheimer's disease: a double‐blind randomized clinical …

M Farokhnia, M Shafiee Sabet… - Human …, 2014 - Wiley Online Library
Objectives Limited pharmacological options are available for the management of
Alzheimer's disease (AD) in severe stages. Cognitive‐enhancing properties of saffron, the …

Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16‐week, randomized and placebo‐controlled trial

S Akhondzadeh, MS Sabet… - Journal of clinical …, 2010 - Wiley Online Library
What is known: Herbal medicines have been used in the treatment of behavioural and
psychological symptoms of dementia but with variable response. Crocus sativus (saffron) …

Therapeutic potential of saffron in brain disorders: From bench to bedside

E Bej, AR Volpe, P Cesare, A Cimini… - Phytotherapy …, 2024 - Wiley Online Library
Saffron is a spice derived from the flower of Crocus sativus L., which has been used for
centuries as a coloring and flavoring agent, as well as a source of medicinal compounds …

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease

S Akhondzadeh, M Shafiee Sabet, MH Harirchian… - …, 2010 - Springer
Rationale There is increasing evidence to suggest the possible efficacy of Crocus sativus
(saffron) in the management of Alzheimer's disease (AD). Objective The purpose of the …

Neuropharmacology effects of saffron (Crocus sativus) and its active constituents

M Nassiri-Asl, H Hosseinzadeh - Bioactive nutraceuticals and dietary …, 2015 - Elsevier
Saffron is a flowering plant used as a spice and food colorant. It has been used in traditional
medicine for various purposes, such as an analgesic, sedative, expectorant, antidepressant …

[HTML][HTML] Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda, H Hosseinzadeh - Iranian Journal of Basic Medical …, 2022 - ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …