One important factor in reperfusion therapy that may predict a favorable outcome is the early
onset of recanalization. Clot dissolution through intravenous thrombolysis alone may not …

Transcranial Doppler (TCD) is an important tool in the armamentarium of stroke
neurologists. This, bedsides modality, can help in establishing the presence, location, and …

Stroke is a major cause of death and disability globally, with ischemic stroke being the
predominant mechanism. While spontaneous recanalization may occur, significant neuronal …

Ultrasound (US) has emerged as a new tool to treat ischemic stroke. The potential
advantage of US is decreased risk of systemic bleeding complications due to its site-specific …

Reopening of the occluded artery is the primary therapeutic goal in hyperacute ischemic
stroke. Systemic treatment with tissue recombinant plasminogen activator (tPA) has been …

Background. Tissue plasminogen activator (TPA) activity may be enhanced with ultrasound,
potentially 2 MHz transcranial Doppler (TCD). The authors present Phase I data of the …

Object Sonothrombolysis has recently been considered an emerging modality for the
treatment of stroke. The purpose of the present paper was to review randomized clinical …

Intravenous tissue plasminogen activator (tPA) remains the only approved, fastest and
widely feasible treatment of acute ischemic stroke. Systemic tPA induces recanalization of …

Systemic administration of tissue plasminogen activator (tPA) remains the fastest way to
initiate treatment for acute ischemic stroke. The presence of a proximal arterial occlusion …

Rationale Transcranial Doppler (TCD) monitoring during intravenous tissue plasminogen
activator (iv-tPA) infusion increases recanalization rates in acute ischemic stroke. Addition of …