Advances in erlotinib delivery systems: Addressing challenges and exploring opportunities in EGFR-targeted cancer therapies
M Pourmadadi, V Mohammadzadeh… - Inorganic Chemistry …, 2024 - Elsevier
Cancer development in various organs, including the breast, ovary, brain, bladder, colon,
and lung, is frequently connected to disturbances in the epidermal growth factor receptor …
and lung, is frequently connected to disturbances in the epidermal growth factor receptor …
Delivery of erlotinib for enhanced cancer treatment: An update review on particulate systems
Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor that has been approved for
metastatic non-small cell lung cancer and highly aggressive pancreatic cancer. Although …
metastatic non-small cell lung cancer and highly aggressive pancreatic cancer. Although …
Harnessing nanotechnology for enhanced delivery of erlotinib: a dynamic duo in cancer treatment
Erlotinib is a reversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor
that acts by inhibiting signaling pathways, resulting in the disruption of cancerous cell …
that acts by inhibiting signaling pathways, resulting in the disruption of cancerous cell …
Multifaceted role of erlotinib in various cancer: nanotechnology intervention, patent landscape, and advancements in clinical trials
B Mangla, P Mittal, P Kumar, G Aggarwal - Medical Oncology, 2024 - Springer
Erlotinib (ELB) is a tyrosine kinase inhibitor that targets the activity of Epidermal Growth
Factor Receptor (EGFR) protein found in both healthy and cancerous cells. It binds …
Factor Receptor (EGFR) protein found in both healthy and cancerous cells. It binds …
Erlotinib hydrochloride novel drug delivery systems: a mini review unravelling the role of micro-and nanocarriers
C Taiwade, A Fulfager, H Bhargave, G Soni… - Drug Delivery …, 2021 - ingentaconnect.com
Erlotinib is a tyrosine kinase inhibitor and it can treat tumors, such as pancreatic and locally
advanced lung cancer or metastatic cancer. The traditional formulation of erlotinib currently …
advanced lung cancer or metastatic cancer. The traditional formulation of erlotinib currently …
Tumor Inhibition Achieved by Targeting and Regulating Multiple Key Elements in EGFR Signaling Pathway Using a Self‐Assembled Nanoprodrug
Comprehensive understanding of signaling pathways regulating cancer progression has led
to tremendous advances of molecularly targeted therapies. The epidermal growth factor …
to tremendous advances of molecularly targeted therapies. The epidermal growth factor …
Recent advances in boosting EGFR tyrosine kinase inhibitors-based cancer therapy
Q Pan, Y Lu, L Xie, D Wu, R Liu, W Gao… - Molecular …, 2023 - ACS Publications
Epidermal growth factor receptor (EGFR) plays a key role in signal transduction pathways
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …
associated with cell proliferation, growth, and survival. Its overexpression and aberrant …
Active targeting strategy in nanomedicines using anti-EGFR ligands–A promising approach for cancer therapy and diagnosis
As active targeting using nanomedicines establishes itself as a strategy of choice in cancer
therapy, several target receptors or ligands overexpressed in cancer cells have been …
therapy, several target receptors or ligands overexpressed in cancer cells have been …
Advances in nanotechnology-based delivery systems for EGFR tyrosine kinases inhibitors in cancer therapy
X Zhou, K Shi, Y Hao, C Yang, R Zha, C Yi… - Asian journal of …, 2020 - Elsevier
Oral tyrosine kinase inhibitors (TKIs) against epidermal growth factor receptor (EGFR) family
have been introduced into the clinic to treat human malignancies for decades. Despite …
have been introduced into the clinic to treat human malignancies for decades. Despite …
Physicochemical properties of epidermal growth factor receptor inhibitors and development of a nanoliposomal formulation of gefitinib
BJ Trummer, V Iyer, SV Balu-Iyer, R O'Connor… - Journal of …, 2012 - Elsevier
Inhibitors of epidermal growth factor (EGF) receptor (EGFR) tyrosine kinases show efficacy
in cancers that are highly addicted to nonmutated EGF signaling, but off-target effects limit …
in cancers that are highly addicted to nonmutated EGF signaling, but off-target effects limit …