Alzheimer's Disease (AD) is a prevalent neurodegenerative disease characterized by tau
hyperphosphorylation, Aβ1-42 aggregation and cognitive dysfunction. Therapeutic agents …

Patients with Alzheimer's disease (AD), a common dementia among the aging population,
often also suffer from depression. This comorbidity is poorly understood. Although most …

Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …

Depression is a major psychiatric disease affecting all ages and is often co-morbid with
neurodegeneration in the elderly. Depression and neurodegeneration are associated with …

Alzheimer's disease (AD) continues to be the most common cause of cognitive and motor
alterations in the aging population. Accumulation of amyloid β (Aβ)-protein oligomers and …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid beta
(Aβ) deposits, hyperphosphorylated tau deposition, and cognitive dysfunction. Abnormalities …

Nerve growth factor (NGF) is an important nerve cell growth regulatory factor and has an
indispensable role in the development, survival and regeneration of the cholinergic basal …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder of
middle-aged to old individuals. The pathophysiological process of AD is believed to begin …

Background A devastating aspect of Alzheimer's disease (AD) is the progressive
deterioration of memory due to neuronal loss. Amyloid precursor protein (APP) occupies a …

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by impairments in synaptic plasticity and cognitive performance. Cognitive …