BACKGROUND Patients with advanced primary and recurrent salivary duct carcinoma
(SDC), a rare and lethal malignancy, have limited therapeutic options. Novel small‐molecule …

Salivary duct carcinoma (SDC) is an aggressive malignancy that frequently presents at an
advanced stage. Mutations/amplification of the gene encoding the p110α catalytic subunit of …

Background: Activity of the tumour-suppressor gene PTEN is reduced in different types of
cancer and implicates non-responsiveness to targeted therapy. This study evaluates the …

The molecular characteristics of therapeutically-relevant targets and their clinicopathological
implications in salivary duct carcinomas (SDCs) are poorly understood. We investigated the …

Background Salivary duct carcinomas (SDCa) are rare highly aggressive malignancies.
Most patients die from distant metastatic disease within three years of diagnosis. There are …

Purpose: Salivary duct carcinomas (SDC) are a rare and aggressive subtype of salivary
gland cancers for which cytotoxic chemotherapy has limited efficacy. We investigated …

Background Salivary duct carcinoma (SDC) is a highly aggressive subtype of salivary gland
cancers and there is no established standard therapy for this disease. Thus, development of …

Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy, which often
presents at an advanced stage. A proportion of SDC are characterized by HER2 …

Salivary gland carcinomas encompass a wide spectrum of histological entities. To identify
candidate therapeutic targets and innovative treatment options for these carcinomas, we …

Purpose: We sought to identify genomic alterations (GA) in salivary gland adenocarcinomas,
not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic …