The study and characterisation of perfusion pressure on decellularisation of porcine oesophagi

WYK Lim - 2020 - dr.ntu.edu.sg
In the field of tissue engineering, new forms of materials for oesophageal reconstruction are
being utilized. Specifically, scaffolds derived from the decellularised extracellular matrix …

Regenerative medicine for oesophageal reconstruction after cancer treatment

KS Chian, MF Leong, K Kono - The Lancet Oncology, 2015 - thelancet.com
Removal of malignant tissue in patients with oesophageal cancer and replacement with
autologous grafts from the stomach and colon can lead to problems. The need to reduce …

Tissue-engineered graft for circumferential esophageal reconstruction in rats

IG Kim, Y Wu, SA Park, H Cho, JW Shin… - JoVE (Journal of …, 2020 - jove.com
The use of biocompatible materials for circumferential esophageal reconstruction is a
technically challenging task in rats and requires an optimal implant technique with nutritional …

Esophagus tissue engineering: from decellularization to in vivo recellularization in two sites

S Eftekharzadeh, A Akbarzadeh, N Sabetkish… - Cell and tissue …, 2022 - Springer
To produce an esophageal scaffold with suitable features and evaluate the result of in vivo
cell seeding after its implantation in the omentum and near its original anatomical position in …

Experimental replacement of the thoracic esophagus with a bioabsorbable collagen sponge scaffold supported by a silicone stent in dogs

Y Yamamoto, T NAKAMURA, Y Shimizu… - ASAIO …, 1999 - journals.lww.com
We manufactured an esophageal prosthesis made of a collagen sponge supported by an
inner silicone tube. The collagen was derived from porcine skin and was crosslinked by …

Tissue engineering of the esophagus

P Maghsoudlou, S Eaton, P De Coppi - Seminars in Pediatric Surgery, 2014 - Elsevier
Esophageal atresia occurs in 1 out of 3000 births. Current treatments involve esophageal
replacement by using more distal parts of the gastrointestinal tract, such as the stomach …

Segmental neogenesis of the dog esophagus utilizing a biodegradable polymer framework

MF Grower, EA Russell, DE Cutright - Biomaterials, artificial cells …, 1989 - Taylor & Francis
This study evaluated the ability of biodegradable implants fabricated from polymers and co-
polymers of polylactic acid (PLA) and polyglycolic acid (PGA) to induce regeneration of …

Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

L Urbani, C Camilli, DE Phylactopoulos… - Nature …, 2018 - nature.com
A tissue engineered oesophagus could overcome limitations associated with oesophageal
substitution. Combining decellularized scaffolds with patient-derived cells shows promise for …

The gastroesophageal junction–A gap in tissue engineering

C Vogt, I Diaz-Gutierrez… - Journal of Immunology and …, 2023 - Elsevier
The gastroesophageal junction (GEJ) plays a critical role in preventing reflux of stomach
contents into the esophagus and airways, but currently there are no options for replacement …

Progress on materials and scaffold fabrications applied to esophageal tissue engineering

Q Shen, P Shi, M Gao, X Yu, Y Liu, L Luo… - Materials Science and …, 2013 - Elsevier
The mortality rate from esophageal disease like atresia, carcinoma, tracheoesophageal
fistula, etc. is increasing rapidly all over the world. Traditional therapies such as surgery …