Melatonin protects against Mdivi-1-induced abnormal spindle assembly and mitochondrial superoxide production during porcine oocyte maturation
SG Yang, SY Joe, JW Bae, GD Heo, HJ Park… - Frontiers in cell and …, 2021 - frontiersin.org
Mitochondrial division inhibitor 1 (Mdivi-1) reportedly provides a close connection between
oocyte maturation and mitochondrial function in pigs. N-acetyl-5-methoxy-tryptamine …
oocyte maturation and mitochondrial function in pigs. N-acetyl-5-methoxy-tryptamine …
Melatonin Promotes in vitro Development of Vitrified-Warmed Mouse GV Oocytes, Potentially by Modulating Phosphorylation of Drp1
J Qin, S Guo, J Yang, IH Qazi, B Pan, T Lv… - Frontiers in Veterinary …, 2021 - frontiersin.org
Previous studies have shown that melatonin can mitigate cryopreservation-induced
mitochondrial dysfunction in oocytes; however, the underlying molecular mechanism …
mitochondrial dysfunction in oocytes; however, the underlying molecular mechanism …
Mdivi-1, mitochondrial fission inhibitor, impairs developmental competence and mitochondrial function of embryos and cells in pigs
JY Yeon, SH Min, HJ Park, JW Kim, YH Lee… - … of Reproduction and …, 2015 - jstage.jst.go.jp
Mitochondria are highly dynamic organelles that undergo constant fusion/fission as well as
activities orchestrated by large dynamin-related GTPases. These dynamic mitochondrial …
activities orchestrated by large dynamin-related GTPases. These dynamic mitochondrial …
Melatonin rescues dimethoate exposure-induced meiotic and developmental defects of porcine oocytes
Q Jiang, X Qi, C Ding, X Liu, Y Lei, S Li, Z Cao - Animals, 2022 - mdpi.com
Simple Summary Environmental pollution poses concerns for public health. Dimethoate is a
pesticide widely used in agricultural fields and home gardens. Recent studies have shown …
pesticide widely used in agricultural fields and home gardens. Recent studies have shown …
Mito-TEMPO protects preimplantation porcine embryos against mitochondrial fission-driven apoptosis through DRP1/PINK1-mediated mitophagy
SG Yang, JW Bae, HJ Park, DB Koo - Life Sciences, 2023 - Elsevier
Abstract Aims Mdivi-1 (Md-1) is a well-known inhibitor of mitochondrial fission and
mitophagy. The mitochondrial superoxide scavenger Mito-TEMPO (MT) exerts positive …
mitophagy. The mitochondrial superoxide scavenger Mito-TEMPO (MT) exerts positive …
DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation
H Zhang, Z Pan, J Ju, C Xing, X Li, M Shan… - Journal of Animal …, 2020 - Springer
Background Environmental pollution induces oxidative stress and apoptosis in mammalian
oocytes, which can cause defects in reproduction; however, the molecular regulation of …
oocytes, which can cause defects in reproduction; however, the molecular regulation of …
[HTML][HTML] Mitochondria of Porcine Oocytes Synthesize Melatonin, Which Improves Their In Vitro Maturation and Embryonic Development
T Zhu, L Yan, S Deng, W Ma, F Xia, L Wang, X Ma, G Li… - Antioxidants, 2024 - mdpi.com
The in vitro maturation efficiency of porcine oocytes is relatively low, and this limits the
production of in vitro porcine embryos. Since melatonin is involved in mammalian …
production of in vitro porcine embryos. Since melatonin is involved in mammalian …
Tyrphostin A9 improves blastocyst development in porcine embryos through induction of dynamin-related protein 1-dependent mitochondrial fission
JH Ahn, HJ Park, JW Kim, JY Park, SY Park, SG Yang… - Mitochondrion, 2017 - Elsevier
Mitochondrial dynamics are associated with the development of porcine embryos. However,
little is known about the effects of mitochondrial dynamics-related genes (Drp1 and pDrp1 …
little is known about the effects of mitochondrial dynamics-related genes (Drp1 and pDrp1 …
Melatonin‐induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence
B He, C Yin, Y Gong, J Liu, H Guo… - Journal of cellular …, 2018 - Wiley Online Library
Melatonin, the major pineal secretory product, has a significant impact on the female
reproductive system. Recently, the beneficial effects of melatonin on mammalian oocyte …
reproductive system. Recently, the beneficial effects of melatonin on mammalian oocyte …
SIRT3 Regulates Levels of Deacetylated SOD2 to Prevent Oxidative Stress and Mitochondrial Dysfunction During Oocyte Maturation in Pigs
L Jiao, CX Hu, Y Zhang, YX Zhang… - Microscopy and …, 2023 - academic.oup.com
Mammalian oocyte maturation relies on mitochondrial ATP production, but this can lead to
damaging reactive oxygen species (ROS). SIRT3, a mitochondrial sirtuin, plays a critical role …
damaging reactive oxygen species (ROS). SIRT3, a mitochondrial sirtuin, plays a critical role …
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