Antibody‐secreting cells (ASC) are the effectors of protective humoral immunity and the only
cell type that produces antibodies or immunoglobulins in mammals. In addition to their …

Antibody secreting cells (ASCs) are terminally differentiated cells of the humoral immune
response and must adapt morphologically, transcriptionally, and metabolically to maintain …

Durable humoral immunity is dependent upon the generation of antigen-specific antibody
titers, produced by non-proliferating bone marrow resident long-lived plasma cells (LLPC) …

Plasma cells (PC) are key to protective immunity because they secrete antibodies. Surviving
for periods ranging from days to decades in mammals, PC possess varying survival times …

Plasma cells are unique immune effectors, capable of producing large amounts of high-
affinity antibodies that protect against pathogenic infections. Although most plasma cells …

Antibody‐secreting plasma cells are a central component of short‐and long‐term adaptive
immunity. Yet, many fundamental questions about how activated B cells decide to yield …

Plasma cells (PCs), the B lineage cells responsible for producing and secreting antibodies
(Abs), are critical cellular components of the humoral immune system. While most of the …

Antibodies produced by antibody-secreting plasma cells (ASCs) underlie multiple forms of
long-lasting immunity. Here we examined the mechanisms regulating ASC turnover and …

Antibodies continuously secreted by plasma cells play a central role in humoral immune
protection of the organism. These plasma cells are generated during the germinal center …

Prophylactic, serological memory relies on maintaining stable reservoirs of plasma cells,
capable of constitutively‐secreting high‐affinity, anti‐pathogen antibody for a lifetime …