Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid beta
(Aβ) deposits, hyperphosphorylated tau deposition, and cognitive dysfunction. Abnormalities …

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family, which
plays important roles in learning and memory formation and in protecting neurons from …

J. Neurochem.(2011) 116, 205–216. Abstract Abundant studies have shown possible links
between low levels of brain‐derived neurotrophic factor (BDNF) and neurological diseases …

Nerve growth factor (NGF) is an important nerve cell growth regulatory factor and has an
indispensable role in the development, survival and regeneration of the cholinergic basal …

Background The use of neurotrophic factors to treat Alzheimer's disease (AD) is hindered by
their blood–brain barrier impermeability, short half-life, and severe side effects. Peptide 021 …

Neurotrophins, including brain‐derived neurotrophic factor (BDNF), nerve growth factor
(NGF), and neurotrophin‐3 (NT‐3), have repeatedly been shown to be involved in the …

Accumulation of toxic amyloid-β (Aβ) in the cerebral cortex and hippocampus is a major
pathological feature of Alzheimer's disease (AD). The neurotrophin receptor p75NTR has …

Besides the presence of amyloid beta (Aβ) plaques and neurofibrillary tangles,
neurogenesis and synaptic plasticity are markedly impaired in Alzheimer's disease (AD) …

Two major neurotrophic factors, nerve growth factor (NGF) and brain-derived neurotrophic
factor (BDNF) are involved in a number of physiological processes associated with neuronal …

Neurotrophins are a family of growth factors that attenuate several forms of pathological
neuronal cell death and may represent a putative therapeutic approach to …