Genotyping of patients to improve pharmacotherapy with chronic gastritis by the MDR1
gene, which provides the pharmacokinetics of drugs used for pharmacotherapy, contributed …

Genotyping of patients to improve pharmacotherapy with chronic gastritis by the MDR1
gene, which provides the pharmacokinetics of drugs used for pharmacotherapy, contributed …

This article discusses the introduction of genotyping of patients with chronic gastritis by
polymorphisms of the MDR-1 gene, especially by polymorphic marker C3435T of this gene …

The article discusses the results of genotyping patients to improve the pharmacotherapy of
acid-dependent diseases of the digestive system by the CYP2C19 gene, which provides the …

The MDR1 gene promotes binding of the cell to the drug, its entry into the cell, and/or efflux
into the intercellular space, which explains the development of resistance of the cell to drugs …

Background There is evidence that changes in MDR1 function and/or expression contribute
to the pathogenesis of inflammatory disorders of the gastrointestinal tract. Aims We aimed to …

In vivo and in vitro studies have demonstrated that P-glycoprotein (P-gp) plays a very
significant role in the ADME processes (absorption, distribution, metabolism, excretion) and …

Background The role of the single nucleotide polymorphisms (SNPs) on positions 2677G>
T/A and 3435C> T of the multi-drug-resistance gene 1 (MDR1) in inflammatory bowel …

The multidrug-resistant transporter encoded by the MDR1 gene belongs to the ATP-binding
cassette superfamily of membrane transporters. It is involved not only in the acquisition of …

The multi-drug resistant transporter MDR1/P-glycoprotein, the gene product of MDR1, is a
glycosylated membrane protein of 170 kDa, belonging to the ATP-binding cassette (ABC) …