Milk fat globule-epidermal growth factor 8 (MFGE8) prevents intestinal fibrosis
S Lin, J Wang, PK Mukherjee, R Mao, G West… - Gut, 2024 - gut.bmj.com
Objective Intestinal fibrosis is considered an inevitable consequence of chronic IBD, leading
to stricture formation and need for surgery. During the process of fibrogenesis, extracellular …
to stricture formation and need for surgery. During the process of fibrogenesis, extracellular …
Proteomic analysis of the inflamed intestinal mucosa reveals distinctive immune response profiles in Crohn's disease and ulcerative colitis
U Berndt, S Bartsch, L Philipsen, S Danese… - The Journal of …, 2007 - journals.aai.org
Abstract Although Crohn's disease (CrD) and ulcerative colitis (UC) share several clinical
features, the mechanisms of tissue injury differ. Because the global cellular function …
features, the mechanisms of tissue injury differ. Because the global cellular function …
Serum Profiling of Proinflammatory Mediators in Inflammatory Bowel Disease: Indication for Use in Differential Diagnosis
A Górecka, G Wisowski, Y Kisselova-Kaneva… - Applied Sciences, 2024 - mdpi.com
Featured Application Featured Application: The aim of our research is to identify biomarkers
with a high specificity and sensitivity for IBD. The identification of new diagnostic methods …
with a high specificity and sensitivity for IBD. The identification of new diagnostic methods …
Intestinal Stromal Cells in the Turmoil of Inflammation and Defective Connective Tissue Remodeling in Inflammatory Bowel Disease
In steady state, intestinal subepithelial myofibroblasts form a thin layer below the basement
membrane. Unlike the rest of the stromal cells in the lamina propria, they express tensile …
membrane. Unlike the rest of the stromal cells in the lamina propria, they express tensile …
Microscopic features for initial diagnosis and disease activity evaluation in inflammatory bowel disease
A Bressenot, K Geboes, JM Vignaud… - Inflammatory bowel …, 2013 - academic.oup.com
Inflammatory bowel disease is characterized by 2 major entities: Crohn's disease (CD) and
ulcerative colitis (UC). In clinical practice, separation of UC and CD has been based on a …
ulcerative colitis (UC). In clinical practice, separation of UC and CD has been based on a …
Alterations of mesenchymal and endothelial cells in inflammatory bowel diseases
The pathogenesis of complex chronic diseases like inflammatory bowel disease (IBD) can
no longer be viewed as a one-way street in which classical immune cells have exclusive …
no longer be viewed as a one-way street in which classical immune cells have exclusive …
[HTML][HTML] Thrombospondin 2, matrix Gla protein and digital analysis identified distinct fibroblast populations in fibrostenosing Crohn's disease
M Jerala, T Remic, N Hauptman, P Homan, N Zajšek… - Scientific Reports, 2024 - nature.com
Fibrosis is an important complication in inflammatory bowel diseases. Previous studies
suggest an important role of matrix Gla protein (MGP) and thrombospondin 2 (THBS2) in …
suggest an important role of matrix Gla protein (MGP) and thrombospondin 2 (THBS2) in …
Emerging biomarkers for the diagnosis and monitoring of inflammatory bowel diseases
AA Soubières, A Poullis - Inflammatory bowel diseases, 2016 - academic.oup.com
There is currently no single test available to confidently diagnose cases of inflammatory
bowel disease (IBD). Physicians rely on a number of diagnostic tools, including clinical …
bowel disease (IBD). Physicians rely on a number of diagnostic tools, including clinical …
Fecal markers in the management of inflammatory bowel disease
C Dai, M Jiang, MJ Sun - Postgraduate medicine, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) is characterized by periods of symptomatic remission and
relapse. Diagnosis and assessment of IBD are based on clinical evaluation, serum …
relapse. Diagnosis and assessment of IBD are based on clinical evaluation, serum …