Characterization of a signaling system in Streptococcus mitis that mediates interspecies communication with Streptococcus pneumoniae

R Junges, K Sturød, G Salvadori… - Applied and …, 2019 - Am Soc Microbiol
Streptococcus mitis is found in the oral cavity and nasopharynx and forms a significant
portion of the human microbiome. In this study, in silico analyses indicated the presence of …

Redundant group a streptococcus signaling peptides exhibit unique activation potentials

B LaSarre, JC Chang, MJ Federle - Journal of bacteriology, 2013 - Am Soc Microbiol
All bacterial quorum sensing (QS) systems are based on the production, secretion, and
detection of small signaling molecules. Gram-positive bacteria typically use small peptides …

Direct interactions with commensal streptococci modify intercellular communication behaviors of Streptococcus mutans

JR Kaspar, K Lee, B Richard, AR Walker… - The ISME …, 2021 - academic.oup.com
The formation of dental caries is a complex process that ultimately leads to damage of the
tooth enamel from acids produced by microbes in attached biofilms. The bacterial …

Interspecies communication among commensal and pathogenic streptococci

LC Cook, B LaSarre, MJ Federle - MBio, 2013 - Am Soc Microbiol
Quorum sensing (QS) regulates diverse and coordinated behaviors in bacteria, including the
production of virulence factors, biofilm formation, sporulation, and competence development …

[HTML][HTML] Effects of expression of streptococcus pneumoniae PspC on the ability of streptococcus mitis to evade complement-mediated immunity

H Marshall, RJ José, M Kilian, FC Petersen… - Frontiers in …, 2021 - frontiersin.org
Streptococcus pneumoniae and Streptococcus mitis are genetically closely related and both
frequently colonise the naso-oropharynx, yet S. pneumoniae is a common cause of invasive …

Origins of heterogeneity in Streptococcus mutans competence: interpreting an environment-sensitive signaling pathway

SJ Hagen, M Son - Physical biology, 2017 - iopscience.iop.org
Bacterial pathogens rely on chemical signaling and environmental cues to regulate disease-
causing behavior in complex microenvironments. The human pathogen Streptococcus …

Human serum supplementation promotes Streptococcus mitis growth and induces specific transcriptomic responses

Y Wei, CI Sturges, KL Palmer - Microbiology Spectrum, 2023 - Am Soc Microbiol
Streptococcus mitis is a normal member of the human oral microbiota and a leading
opportunistic pathogen causing infective endocarditis (IE). Despite the complex interactions …

[HTML][HTML] PcsB Expression Diversity Influences on Streptococcus mitis Phenotypes Associated With Host Persistence and Virulence

EN Harth-Chu, LA Alves, JD Theobaldo… - Frontiers in …, 2019 - frontiersin.org
S. mitis is an abundant member of the commensal microbiota of the oral cavity and pharynx,
which has the potential to promote systemic infections. By analyzing a collection of S. mitis …

Interspecies communication in Streptococcus gordonii–Veillonella atypica biofilms: Signaling in flow conditions requires juxtaposition

PG Egland, RJ Palmer Jr… - Proceedings of the …, 2004 - National Acad Sciences
During the development of human oral biofilm communities, the spatial arrangement of the
bacteria is thought to be driven by metabolic interactions between them. Streptococcus …

Capsule expression in Streptococcus mitis modulates interaction with oral keratinocytes and alters susceptibility to human antimicrobial peptides

HV Rukke, SA Engen, K Schenck… - Molecular oral …, 2016 - Wiley Online Library
Streptococcus mitis is a colonizer of the oral cavity and the nasopharynx, and is closely
related to Streptococcus pneumoniae. Both species occur in encapsulated and …