Rgg-associated SHP signaling peptides mediate cross-talk in Streptococci

B Fleuchot, A Guillot, C Mezange, C Besset… - PLoS …, 2013 - journals.plos.org
We described a quorum-sensing mechanism in the streptococci genus involving a short
hydrophobic peptide (SHP), which acts as a pheromone, and a transcriptional regulator …

A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation

RA Cuevas, R Eutsey, A Kadam… - Molecular …, 2017 - Wiley Online Library
Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common
colonizer of the human respiratory track, where it utilizes cell–cell communication systems to …

The transcriptional regulator CpsY is important for innate immune evasion in Streptococcus pyogenes

LA Vega, KM Valdes, GS Sundar, AT Belew… - Infection and …, 2017 - Am Soc Microbiol
As an exclusively human pathogen, Streptococcus pyogenes (the group A streptococcus
[GAS]) has specifically adapted to evade host innate immunity and survive in multiple tissue …

One if by land, two if by sea: signalling to the ranks with CSP and XIP

MJ Federle, DA Morrison - Molecular microbiology, 2012 - Wiley Online Library
In many streptococci, quorum sensing utilizes secreted, linear peptides that engage cognate
receptors to coordinate gene expression among members of a local population. S …

Streptococcus mitis: walking the line between commensalism and pathogenesis

J Mitchell - Molecular oral microbiology, 2011 - Wiley Online Library
Streptococcus mitis is a viridans streptococcus and a normal commensal of the human
oropharynx. However, S. mitis can escape from this niche and cause a variety of infectious …

Identification of virulence-associated properties by comparative genome analysis of Streptococcus pneumoniae, S. pseudopneumoniae, S. mitis, three S. oralis …

M Kilian, H Tettelin - MBio, 2019 - Am Soc Microbiol
From a common ancestor, Streptococcus pneumoniae and Streptococcus mitis evolved in
parallel into one of the most important pathogens and a mutualistic colonizer of humans …

Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus

N Makthal, H Do, AR VanderWal, RJ Olsen… - Infection and …, 2018 - Am Soc Microbiol
Bacterial virulence factor production is a highly coordinated process. The temporal pattern of
bacterial gene expression varies in different host anatomic sites to overcome niche-specific …

Intracellular Streptococcus pyogenes in Human Macrophages Display an Altered Gene Expression Profile

E Hertzén, L Johansson, R Kansal, A Hecht, S Dahesh… - PloS one, 2012 - journals.plos.org
Streptococcus pyogenes is an important human pathogen, which has recently gained
recognition as an intracellular microorganism during the course of severe invasive infections …

Transcriptome analyses extend understanding of Streptococcus pyogenes regulatory mechanisms and behavior toward immunomodulatory substances

C Riani, K Standar, S Srimuang, C Lembke… - International Journal of …, 2007 - Elsevier
The recent genome sequencing of several Streptococcus pyogenes serotype strains
allowed the design of corresponding DNA microarrays and their usage for specific …

Streptococcus pyogenes forms serotype-and local environment-dependent interspecies protein complexes

S Chowdhury, H Khakzad, GE Bergdahl, R Lood… - Msystems, 2021 - Am Soc Microbiol
Streptococcus pyogenes is known to cause both mucosal and systemic infections in
humans. In this study, we used a combination of quantitative and structural mass …