Parkinson's disease (PD) is a common neurodegenerative disorder, resulting from
progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by a
slowly progressive motor dysfunction and loss of dopaminergic neurons located in the …

Parkinson's disease (PD) is recognized as the second most common neurodegenerative
disorder after Alzheimer's disease. PD is mainly characterized by a selective degeneration …

Destruction of dopaminergic neurons in the substantia nigra pars compacta (SNpc) is a
common pathophysiology of Parkinson's disease (PD). Characteristics of PD patients …

1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) is known to cause parkinsonism in
humans and this fact is a major incentive for using this toxin as an animal model to study the …

Parkinson's disease (PD) is a common neurodegenerative disease that appears essentially
as a sporadic condition. PD is well known to be a chronic and progressive …

Parkinson's disease (PD) is a progressive neurodegenerative disorder clinically
characterized by cardinal motor deficits including bradykinesia, tremor, rigidity and postural …

Among the popular animal models of Parkinson's disease (PD) commonly used in research
are those that employ neurotoxins, especially 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

Although much progress have been made in recent years, the etiology of idiopathic
Parkinson's disease remains obscure. The chance discovery that injection of the neurotoxin …

Abstract The neurotoxin 1-methyl, 4-phenyl-1, 2, 3, 6-tetrahydropiridine (MPTP) is widely
used to produce experimental parkinsonism in rodents and primates. Among different …