Angiotensin II type 1 receptor antagonists like losartan have been found to lower the
incidence and progression to Alzheimer's disease (AD), as well as rescue cognitive and …

This commentary reviews the role of the Alzheimer amyloid peptide Aβ on basal synaptic
transmission, synaptic short-term plasticity, as well as short-and long-term potentiation in …

Background: T3D-959, a dual PPAR-δ/PPAR nuclear receptor agonist and former diabetes
drug candidate, has been repositioned as an Alzheimer's disease (AD)-modifying therapy …

Adipose tissue has recently been recognized as an important endocrine organ that plays a
crucial role in energy metabolism and in the immune response in many metabolic tissues …

Noradrenergic deficits have been described in the hippocampus and the frontal cortex of
Alzheimer's disease brains, which are secondary to locus coeruleus degeneration. Locus …

Alzheimer's disease (AD) is one of the most serious human, medical, and socioeconomic
burdens. Here we tested the hypothesis that a rat model of AD (Samaritan; Taconic …

Consumption of caffeine, a non-selective adenosine A2A receptor (A2AR) antagonist,
reduces the risk of developing Alzheimer's disease (AD) and mitigates both amyloid and Tau …

This Mini Review discusses the merits and shortfalls of transgenic (tg) rodents modeling
aspects of the human Alzheimer's disease (AD) pathology and their application to evaluate …

Alzheimer's disease (AD) is an age-associated neurodegenerative disease. As the
population ages, the increasing prevalence of AD threatens massive healthcare costs in the …

Sleep disruption is an expected component of aging and neurodegenerative conditions,
including Alzheimer's disease (AD). Sleep disruption has been demonstrated as a driver of …