Amino acids such as leucine and its metabolite α-ketoisocaproate (KIC), are returning to be
the focus of studies, mainly because of their anti-catabolic properties, through inhibition of …

Abstract β-Hydroxy β-methylbutyrate (HMB), a metabolite of the essential amino acid
leucine, is one of the latest dietary supplements promoted to enhance gains in strength and …

Abstract Beta‐hydroxy‐beta‐methylbutyrate (HMB) is a metabolite of the essential amino
acid leucine that has been reported to have anabolic effects on protein metabolism. The …

Key points• The branched‐chain amino acid (BCAA) leucine acts as both a 'trigger'for the
initiation of protein synthesis, and as a substrate for newly synthesized protein.• As a BCAA …

Branched-chain amino acids (BCAA) are one of the most popular sports supplements,
marketed under the premise that they enhance muscular adaptations. Despite their …

Beta-hydroxy-beta-methylbutyrate (HMB) has been used extensively as a dietary
supplement for athletes and physically active people. HMB is a leucine metabolite, which is …

Abstract Nissen, S., R. Sharp, M. Ray, JA Rathmacher, D. Rice, JC Fuller, Jr., AS Connelly,
and N. Abumrad. Effect of leucine metabolite β-hydroxy-β-methylbutyrate on muscle …

Abstract Beta-hydroxy-beta-methylbutyrate (HMB), a metabolite of the branched-chain
amino acid leucine, is extensively used by athletes and bodybuilders in order to increase …

Introduction: although β-hydroxy-β-methylbutyrate (HMB) is generally marketed as a
supplement for increasing muscle mass and strength, it is still not fully understood how and …

β-hydroxy-β-methylbutyrate (HMB) is a metabolite derived from leucine and its ketoacid
alpha-ketoisocaproate. Leucine has a role in regulating protein synthesis in muscle cells …