The impact of amyloid-β or tau on cognitive change in the presence of severe cerebrovascular disease

H Jang, HJ Kim, YS Choe, SJ Kim… - Journal of …, 2020 - content.iospress.com
Background: As Alzheimer's disease (AD) and cerebral small vessel disease (CSVD)
commonly coexist, the interaction between two has been of the considerable interest …

Brain amyloid β, cerebral small vessel disease, and cognition: A memory clinic study

FN Saridin, S Hilal, SG Villaraza, A Reilhac… - Neurology, 2020 - AAN Enterprises
Objective To evaluate the association between brain amyloid β (Aβ) and cerebral small
vessel disease (CSVD) markers, as well as their joint effect on cognition, in a memory clinic …

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

I Bos, FR Verhey, IHGB Ramakers, HIL Jacobs… - Alzheimer's research & …, 2017 - Springer
Background Cerebrovascular disease (CVD) and amyloid-β (Aβ) often coexist, but their
influence on neurodegeneration and cognition in predementia stages remains unclear. We …

Effects of amyloid and vascular markers on cognitive decline in subcortical vascular dementia

BS Ye, SW Seo, JH Kim, GH Kim, H Cho, Y Noh… - Neurology, 2015 - AAN Enterprises
Objective: To determine the independent and synergistic effects of amyloid and small vessel
disease (SVD) burden on longitudinal cognitive decline in patients with subcortical vascular …

Contributions of amyloid beta and cerebral small vessel disease in clinical decline

JEF Moonen, R Haan, I Bos, C Teunissen… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We assessed whether co‐morbid small vessel disease (SVD) has clinical
predictive value in preclinical or prodromal Alzheimer's disease. METHODS In 1090 non …

Distinct cerebral small vessel disease impairment in early‐and late‐onset Alzheimer's disease

X Luo, H Hong, K Li, Q Zeng, S Wang… - Annals of Clinical …, 2023 - Wiley Online Library
Objective This study investigated cerebral small vessel disease (CSVD) damage patterns in
early‐onset and late‐onset Alzheimer's disease (EOAD and LOAD) and their effects on …

White matter lesions may be an early marker for age-related cognitive decline

C Morrison, M Dadar, S Villeneuve, DL Collins - NeuroImage: Clinical, 2022 - Elsevier
Background Research suggests that cerebral small vessel disease (CSVD), amyloid, and
pTau contribute to age-related cognitive decline. It remains unknown how these factors …

Increased CSF levels of total Tau in patients with subcortical cerebrovascular pathology and cognitive impairment

M Radanovic, F Stella, LG Silva, LL Talib… - Dementia & …, 2017 - SciELO Brasil
Cognitive impairment includes mild cognitive decline and dementia, such as Alzheimer's
disease (AD) and cerebrovascular-related pathologies. Objective: To investigate the profile …

Interaction between Alzheimer's disease and cerebral small vessel disease: A review focused on neuroimaging markers

SE Kim, HJ Kim, H Jang, MW Weiner… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is characterized by the presence of β-amyloid (Aβ) and tau, and
subcortical vascular cognitive impairment (SVCI) is characterized by cerebral small vessel …

[HTML][HTML] The cognitive dysfunction related to Alzheimer disease or cerebral small vessel disease: What's the differences

Z Liang, L Wu, S Gong, X Liu - Medicine, 2021 - journals.lww.com
Alzheimer disease (AD) and sporadic cerebral small vessel disease (CSVD) are common
cognitive disorders. Both AD and CSVD have mental symptoms including chronic …